Evidence map›Paper›PMID 30685842›Full record

ArticleMolecular neurobiology2019

Impaired Pentose Phosphate Pathway in the Spinal Cord of the hSOD1

Tesfaye Wolde Tefera, Katherine Bartlett, Shirley S Tran, Mark P Hodson, Karin Borges

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tesfaye Wolde TeferaNeurological Disorders and Metabolism Lab, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.
Katherine BartlettNeurological Disorders and Metabolism Lab, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.
Shirley S TranNeurological Disorders and Metabolism Lab, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia.
Mark P HodsonMetabolomics Australia Queensland Node, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia.
Karin BorgesNeurological Disorders and Metabolism Lab, School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia. k.borges@uq.edu.au.ORCID http://orcid.org/0000-0001-7448-0770
The University of Queensland · AU

Funding

Motor Neurone Disease Research Institute of Australia GIA 1704
6 · The paper itself

Abstract

Impairments in energy metabolism in amyotrophic lateral sclerosis (ALS) have long been known. However, the changes in the energy-producing pathways in ALS are not comprehensively understood. To investigate specific alterations in glucose metabolism in glycolytic, pentose phosphate, and TCA cycle pathways, we injected uniformly labeled [U-

Indexed as

Pentose Phosphate PathwayAmyotrophic Lateral SclerosisAnimalsCitric Acid CycleDisease Models, AnimalGlycolysisHumansMaleMetabolomeMice, Inbred C57BLMice, TransgenicModels, BiologicalSpinal CordSuperoxide Dismutase-1Superoxide Dismutase-1Energy metabolismGlycolysisLiquid chromatography-tandem mass spectrometryMotor neuron diseasePentose phosphate pathwayTCA cycle

Identifiers

PMID30685842
OpenAlexW2911590944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.