Evidence map›Paper›PMID 30685353›Full record

ReviewNeurobiology of disease2019

Child maltreatment and psychosis.

Joan Kaufman, Souraya Torbey

Abstract readReview
In one paragraph

Review in Neurobiology of disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joan KaufmanKennedy Krieger Institute, Center for Child and Family Traumatic Stress, 1741 Ashland Avenue, Baltimore, MD 21205, United States; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States. Electronic address: joan.kaufman@kennedykrieger.org.
Souraya TorbeyDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States.

Funding

Social adversities, epigenetics, and the obesity epidemicR01MD011746 · NIMHD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI HOYO, CATHRINE · 2017 to 2021
$4.4M
Risk and Resilience in Maltreated ChildrenR01MH098073 · NIMH · YALE UNIVERSITY · PI HUDZIAK, JAMES J., KAUFMAN, JOAN R. · 2012 to 2015
$3.0M
NIMHD NIH HHS R01 MD011746NIMH NIH HHS R01 MH098073
6 · The paper itself

Abstract

This paper reviews the literature on the association between experiences of child abuse and neglect and the development of psychoses. It then explores the premise that psychotic patients with a history of maltreatment may comprise a clinically and biological distinct subgroup. The review demonstrates that there is a growing consensus in the field that experiences of child maltreatment contribute to the onset of psychotic symptoms and psychotic disorders. There is also strong support for the premise that patients with psychotic disorders and histories of child maltreatment have distinct clinical characteristics and unique treatment needs, and emerging preliminary data to suggest psychotic patients with a history of maltreatment may comprise a distinct neurobiological subgroup. The mechanisms by which experiences of child maltreatment confers risk for psychotic disorders remains unknown, and the review highlights the value of incorporating translational research perspectives to advance knowledge in this area.

Indexed as

ChildChild AbuseFemaleHumansMalePsychotic Disorders

Identifiers

PMID30685353
PMCPMC6656637

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.