Evidence map›Paper›PMID 30684784›Full record

ArticleComputers in biology and medicine2019

Motor unit innervation zone localization based on robust linear regression analysis.

Jie Liu, Sheng Li, Faezeh Jahanmiri-Nezhad, William Zev Rymer, Ping Zhou

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jie LiuSensory Motor Performance Program, Shirley Ryan AbilityLab, Chicago, United States; Kay Mounting Service Ltd, London, United Kingdom. Electronic address: jie.liu2009@gmail.com.
Sheng LiDepartment of Physical Medicine and Rehabilitation, University of Texas Health Science Center at Houston, Houston, United States; TIRR Memorial Hermann Research Center, Houston, TX, United States.
Faezeh Jahanmiri-NezhadSensory Motor Performance Program, Shirley Ryan AbilityLab, Chicago, United States; Department of Bioengineering, University of Illinois at Chicago, Chicago, United States.
William Zev RymerSensory Motor Performance Program, Shirley Ryan AbilityLab, Chicago, United States; Department of Physical Medicine & Rehabilitation, Northwestern University, Chicago, United States.
Ping ZhouDepartment of Physical Medicine and Rehabilitation, University of Texas Health Science Center at Houston, Houston, United States; TIRR Memorial Hermann Research Center, Houston, TX, United States.
Shirley Ryan AbilityLab · USMemorial Hermann Institute for Rehabilitation and Research Foundation · USThe University of Texas Health Science Center at Houston · US

Funding

Noninvasive High-resolution Pediatric Surface EMGR21NS093727 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, PING · 2016 to 2017
$424k
Degeneration of motoneurons caudal to spinal lesionR21NS075463 · NINDS · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI RYMER, WILLIAM ZEV, ZHOU, PING · 2012 to 2013
$418k
NINDS NIH HHS R21 NS075463NINDS NIH HHS R21 NS093727
6 · The paper itself

Abstract

With the aim of developing a flexible and reliable procedure for superficial muscle innervation zone (IZ) localization, we proposed a method to estimate IZ location using surface electromyogram (EMG) based on robust linear regression. Regression lines were used to model the bidirectional propagation pattern of a single motor unit action potential (MUAP) and visualize the trajectory of the MUAP propagation. IZ localization was performed by identifying the origin of the bidirectional MUAP propagation. Robust linear regression and MUAP peak detection, combined with propagation phase reversal identification, may provide an efficient way to estimate IZ location. Our method offers high resolution in locating IZs based on simulation studies and experimental tests. Furthermore, our method is flexible and may also be applied using a relatively small number of EMG channels. A comparative study of the proposed method with the cross-correlation method for IZ localization was conducted. The results obtained with simulated MUAPs and measured spontaneous MUAPs in the biceps brachii muscle in six subjects (four males and two females, 57 ± 10 years old) with amyotrophic lateral sclerosis (ALS). Our method achieved estimation performance comparable to that obtained by using the cross-correlation method but with higher resolution. This study provides an accurate and practical method to estimate IZ location.

Indexed as

ElectromyographyMuscle, SkeletalAction PotentialsAgedFemaleHumansMaleMiddle AgedMuscle ContractionRegression AnalysisInnervation zone (IZ)Motor unit action potential (MUAP)Robust linear regression

Identifiers

PMID30684784
PMCPMC6392055
OpenAlexW2909174594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.