ArticleWorld neurosurgery2019
Venous Thromboembolism After Degenerative Spine Surgery: A Nationwide Readmissions Database Analysis.
Article in World neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- The Risk of Venous Thromboembolism after Thoracolumbar Spine Surgery: A Population-Based Cohort Study.Journal of clinical medicine · 2023Article
- Tobacco Use Is Associated With Increased 90-Day Readmission Among Patients Undergoing Surgery for Degenerative Spine Disease.Global spine journal · 2022Article
- Venous Thromboembolism Prophylaxis in Elective Spine Surgery.Global spine journal · 2021Article
- Systemic Corticosteroids and the Risk of Venous Thromboembolism in Patients with Severe COPD: A Nationwide Study of 30,473 Outpatients.Biomedicines · 2021Article
- Article
- Lower Activity and Function Scores Are Associated with a Higher Risk of Preoperative Deep Venous Thrombosis in Patients Undergoing Total Hip Arthroplasty.Journal of clinical medicine · 2020Article
- Article
- Identification of molecular markers for pre-thrombotic state: validation in the rabbits with tibia fracture or lung cancer.Translational cancer research · 2019Article
- A predictive model of preoperative risk factors for venous thromboembolism after fusion for degenerative conditions of the thoracolumbar spine.Journal of orthopaedicsArticle
- Complication rates following Chiari malformation surgical management for Arnold-Chiari type I based on surgical variables: A national perspective.Journal of craniovertebral junction & spineArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundVenous thromboembolism (VTE) is an appreciable burden on health care. The protracted recumbency experienced by many spinal patients juxtaposed with concerns for postoperative hemorrhage from early anticoagulation results in conflicting stances regarding chemoprophylaxis. Identifying risk factors associated with VTE is therefore instrumental in guiding management.
objectiveTo identify VTE risk factors in patients undergoing degenerative spine surgery.
methodsThe Nationwide Readmissions Database was searched for adults undergoing spine surgery for degenerative diseases between 2010 and 2014. The 30-day and 90-day VTE incidence was estimated from readmissions with new VTE diagnoses. A multivariate survey-adjusted logistic regression model was used to identify variables associated with VTE diagnoses on readmission.
resultsOf 838,507 degenerative spine cases queried, 3499 patients (0.42%) were readmitted with a VTE diagnosis within 30 days and 4321 patients (0.62%) were readmitted within 90 days. In multivariate analysis, steroids were independently associated with a higher likelihood of readmission with VTE at both 30 days (odds ratio, 1.58; P < 0.001) and 90 days (odds ratio, 1.97; P < 0.001). Significant associations were also identified with thoracolumbar surgery, length of stay, and discharge to institutional care.
conclusionsThe incidence of readmission with VTE diagnoses in spine surgery is low. However, their devastating consequences underscore the need to identify those patients deemed high risk. These patients include those having thoracolumbar surgery, of advanced age, with prolonged length of stay, using corticosteroids, and with a disposition to institutional care (e.g., skilled nursing facility or long-term acute care). Given the association between steroids and VTE, clinicians should be judicious about perioperative administration despite their obvious antiinflammatory benefits.
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