Evidence map›Paper›PMID 30684406›Full record

ArticleJMIR formative research2018

Web-Delivered Multimedia Training Materials for the Self-Collection of Dried Blood Spots: A Formative Project.

Alicia M Allen, Kim Lundeen, Sharon E Murphy, Logan Spector, Bernard L Harlow

Abstract read
In one paragraph

Article in JMIR formative research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  12. Anti-Müllerian Hormone Levels among Female Firefighters.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alicia M Allen *Department of Family & Community Medicine, College of Medicine, University of Arizona, Tucson, AZ, United States.ORCID http://orcid.org/0000-0002-1007-4949
Kim LundeenDepartment of Family Medicine & Community Health, Medical School, University of Minnesota, Minneapolis, MN, United States.ORCID http://orcid.org/0000-0001-7293-8514
Sharon E MurphyDivision of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, United States.ORCID http://orcid.org/0000-0001-5391-8104
Logan SpectorDivision of Epidemiology and Clinical Research, Pediatrics, University of Minnesota, Minneapolis, MN, United States.ORCID http://orcid.org/0000-0003-2516-0222
Bernard L HarlowDepartment of Epidemiology, School of Public Health, Boston University, Boston, MA, United States.ORCID http://orcid.org/0000-0002-6735-8862

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Univ of Minnesota Buidling Interdisciplinary Research Careers in Women's HealthK12HD055887 · NICHD · UNIVERSITY OF MINNESOTA · PI ALLEN, SHARON S, BERGE, JERICA M · 2007 to 2023
$8.6M
NCATS NIH HHS UL1 TR000114NICHD NIH HHS K12 HD055887
6 · The paper itself

Abstract

backgroundThe use of dried blood spots (DBS) in biomedical research has been increasing as an objective measure for variables that are typically plagued by self-report, such as smoking status and medication adherence. The development of training materials for the self-collection of DBS that can be delivered through the Web would allow for broader use of this methodology.

objectiveThe objective of this study was to evaluate the acceptability and feasibility of the self-collection of DBS using newly developed multimedia training materials that were delivered through the Web. We also aimed to assess the usability of the collected DBS samples.

methodsWe recruited participants through Facebook advertising for two distinct studies. The first study evaluated the acceptability of our newly developed DBS training materials, while the second assessed the implementation of this protocol into a larger Web-based study.

resultsIn the first study, participants (N=115) were aged, on average, 26.1 (SD 6.4) years. Training materials were acceptable (113/115, 98.2%, of participants were willing to collect DBS again) and produced usable samples (110/115, 95.7%, collected DBS were usable). In the second study, response rate was 25.0% (41/164), with responders being significantly younger than nonresponders (20.3 [SD 0.2] vs 22.0 [SD 0.4]; P<.001), and 92% (31/41) of collected DBS samples were usable by the laboratory.

conclusionsOverall, while the protocol is acceptable, feasible, and produced usable samples, additional work is needed to improve response rates.

Indexed as

dried blood spotfeasibility studiesinternet

Identifiers

PMID30684406
PMCPMC6334672

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.