ArticleJMIR formative research2018
Web-Based Tailored Intervention to Support Optimal Medication Adherence Among Kidney Transplant Recipients: Pilot Parallel-Group Randomized Controlled Trial.
Article in JMIR formative research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Tailoring for Health Literacy in the Design and Development of eHealth Interventions: Systematic Review.JMIR human factors · 2025Pooled it
- Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients.The Cochrane database of systematic reviews · 2022Pooled it
- Effect of Interactive eHealth Interventions on Improving Medication Adherence in Adults With Long-Term Medication: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Effectiveness of IT-based interventions on self-management in adult kidney transplant recipients: a systematic review.BMC medical informatics and decision making · 2021Pooled it
- Cost-utility analysis of a web-based interactive patient education platform: evidence from a randomized clinical trial for end-stage renal disease patients.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Trial
- Self-Management Interventions for Kidney Transplant Recipients: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Determining the Relationship Between Perceived Social Support and Immunosuppressive Medication Adherence After Kidney Transplantation: A Descriptive Correlational Study.Journal of evaluation in clinical practice · 2025Article
- Technology-Enabled Remote Patient Monitoring and Education to Improve Kidney Transplant Knowledge, Access, and Post-Transplant Care: A Narrative Review.Current transplantation reports · 2025Article
- Exploring the relationship between website quality and equity in living donor kidney transplant.Frontiers in transplantation · 2024Article
- Advanced Messaging Intervention for Medication Adherence and Clinical Outcomes Among Patients With Cancer: Randomized Controlled Trial.JMIR cancer · 2023Article
- Rehabilitation, the Great Absentee of Virtual Coaching in Medical Care: Scoping Review.Journal of medical Internet research · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptimal immunosuppressive medication adherence is essential to graft survival. Transplant-TAVIE is a Web-based tailored intervention developed to promote this adherence.
objectiveThe objective of our study was to evaluate the Transplant-TAVIE intervention's acceptability, feasibility, and preliminary efficacy.
methodsIn a pilot, parallel-group, randomized controlled trial, we randomly assigned a convenience sample of 70 kidney transplant patients on immunosuppressive medication either to an experimental group (Transplant-TAVIE) or to a control group (existing websites). Kidney transplant recipients had to be older than 18 years, be taking immunosuppressant medication, and have access to the internet to participate in this study. Transplant-TAVIE was composed of three interactive Web-based sessions hosted by a virtual nurse. We documented user appreciation of and exposure to the intervention. Furthermore, we assessed medication adherence, medication self-efficacy, intake-related skills, and medication side effects at baseline and 3 and 6 months later. Analyses of variance were used to assess intergroup differences over time.
resultsAfter baseline questionnaire completion, participants were randomly assigned either to Transplant-TAVIE (n=35) or to the websites (n=35) group. All participants had received their kidney graft <1 year to 32 years earlier (mean 6.8 years). Of the experimental group, 54% (19/35) completed the sessions of Transplant-TAVIE. Users found the intervention to be acceptable-33% were extremely satisfied (6/18), 39% were very satisfied (7/18), and 28% were satisfied (5/18). At baseline and over time, both experimental and control groups reported high medication adherence, high medication self-efficacy, and frequent use of skills related to medication intake. No intergroup differences emerged over time.
conclusionsThe results of this study support the feasibility and acceptability of Transplant-TAVIE. It could constitute an accessible adjunct in support of existing specialized services.
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