Evidence map›Paper›PMID 30684097›Full record

ReviewInternal and emergency medicine2019

Update on the treatment of Behçet's syndrome.

Sinem Nihal Esatoglu, Gulen Hatemi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Behçet Disease: An Update for Dermatologists.American journal of clinical dermatology · 2021
    Review
  9. Advances in the Treatment of Behcet's Disease.Current rheumatology reports · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Pediatric Behçet's Disease.Frontiers in medicine · 2021
    Review
  15. Experimental Therapeutic Solutions for Behcet's Disease.Journal of experimental pharmacology · 2021
    Review
  16. [Progress in interferon: A treatment of Behcet syndrome].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Immunopathogenesis of Behcet's Disease.Frontiers in immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sinem Nihal EsatogluDivision of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, 34098, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5414-7305
Gulen HatemiDivision of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, 34098, Istanbul, Turkey. gulenhatemi@yahoo.com.ORCID http://orcid.org/0000-0002-1952-1135
Istanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's syndrome (BS) is a complex disease that shows important heterogeneity in clinical findings and physiopathology. Its treatment can be problematic as BS manifestations in different organs may respond differently to the same drug. The cornerstone of therapy for inducing remission is corticosteroids whereas immunomodulatory and immunosuppressive agents such as colchicine, azathioprine, cyclosporine-A, interferon-alpha, and cyclophosphamide are used as steroid-sparing agents and to prevent further relapses. However, a considerable number of patients continue to have mucocutaneous lesions despite therapy, and some patients require more aggressive treatment for refractory major organ involvement. Tumor necrosis factor alpha inhibitors, especially infliximab and adalimumab, are increasingly used for various refractory BS manifestations despite the lack of controlled studies. In this review, we aim to focus on both the traditional and new treatment modalities for BS, with more emphasis on recent data on newer agents.

Indexed as

AzathioprineBehcet SyndromeColchicineCyclophosphamideCyclosporinsDisease ManagementHumansImmunosuppressive AgentsInterferon-alphaReview Literature as TopicAzathioprineColchicineCyclophosphamideCyclosporinsImmunosuppressive AgentsInterferon-alphaBehçet’s syndromeBiologic agentsManagementTNF inhibitorsTreatment

Identifiers

PMID30684097
OpenAlexW2912113125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.