Evidence map›Paper›PMID 30684069›Full record

ArticleArchives of osteoporosis2019

An observational cohort study to produce and evaluate an improved tool to screen older women with back pain for osteoporotic vertebral fractures (Vfrac): study protocol.

T K Khera, A Burston, S Davis, S Drew, R Gooberman-Hill, Z Paskins, T J Peters, J H Tobias, E M Clark

Open access · hybridAbstract readClinical Trial Protocol
In one paragraph

Article in Archives of osteoporosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

T K KheraBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK. t.khera@bristol.ac.uk.
A BurstonBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
S DavisHealth Economics and Decision Science, University of Sheffield, Sheffield, UK.
S DrewBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
R Gooberman-HillBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
Z PaskinsArthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Staffordshire, ST5 5BG, UK.
T J PetersBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
J H TobiasBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
E M ClarkBristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.
University of Bristol · GBMidlands Partnership NHS Foundation Trust · GBUniversity of Sheffield · GB

Funding

Arthritis Research UK 21507Versus Arthritis 21507
6 · The paper itself

Abstract

The aim of this study is to produce an easy to use checklist for general practitioners to complete whenever a woman aged over 65 years with back pain seeks healthcare. This checklist will produce a binary output to determine if the patient should have a radiograph to diagnose vertebral fracture. PURPOSE: People with osteoporotic vertebral fractures are important to be identified as they are at relatively high risk of further fractures. Despite this, less than a third of people with osteoporotic vertebral fractures come to clinical attention due to various reasons including lack of clear triggers to identify who should have diagnostic spinal radiographs. This study aims to produce and evaluate a novel screening tool (Vfrac) for use in older women presenting with back pain in primary care based on clinical triggers and predictors identified previously. This tool will generate a binary output to determine if a radiograph is required.

methodsThe Vfrac study is a two-site, pragmatic, observational cohort study recruiting 1633 women aged over 65 years with self-reported back pain. Participants will be recruited from primary care in two sites. The Vfrac study will use data from two self-completed questionnaires, a simple physical examination, a lateral thoracic and lateral lumbar radiograph and information contained in medical records.

resultsThe primary objective is to develop an easy-to-use clinical screening tool for identifying older women who are likely to have vertebral fractures.

conclusionsThis article describes the protocol of the Vfrac study; ISRCTN16550671.

Indexed as

AgedAged, 80 and overBack PainCohort StudiesFemaleHumansMass ScreeningMiddle AgedObservational Studies as TopicOsteoporotic FracturesPragmatic Clinical Trials as TopicPrimary Health CareRadiographyRiskSpinal FracturesSpineOsteoporosisProtocolScreeningVertebral fracture

Identifiers

PMID30684069
PMCPMC6347587
OpenAlexW2922873953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.