ArticleInternational archives of occupational and environmental health2019
Blue-yellow dyschromatopsia in toluene-exposed workers.
Article in International archives of occupational and environmental health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Investigating the general effects of different types of toluene exposure on the health of workers: an integrative review of the literature.BMJ public health · 2025Article
- Toluene: MAK Value Documentation, addendum - Translation of the German version from 2021.The MAK collection for occupational health and safety · 2024Review
- Article
- Risk assessment of chemical mixtures by benchmark dose-principle component analysis approach in occupational exposure.Environmental science and pollution research international · 2021Article
- Effect of environmental toxicants on neuronal functions.Environmental science and pollution research international · 2020Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the effects of a chronic occupational exposure to toluene on color vision.
methodsColor vision was tested in 51 workers exposed to pure toluene and in 51 matched control subjects. Current exposure was determined by biological monitoring. Blood samples were taken at the end of a Friday shift. Color vision ability was assessed using the Ishihara plates (to screen for congenital dyschromatopsia), the Farnsworth panel D-15 test, the Lanthony panel D-15 desaturated test, the Velhagen plates, and the Standard Pseudoisochromatic Plates Part 2.
resultsMedian toluene concentration was 1.59 mg/l (quartiles 0.78 and 2.65). The whole group of workers did not perform worse than the controls. The same applies to 20 printers, who regularly assessed hues. Assessed with the most sensitive Lanthony panel D-15 desaturated test, color vision of 24 permanently exposed assistants was impaired (median color confusion index of the 1st eyes 1.08 vs. 1.02, p < 0.02; 2nd eyes 1.08 vs. 1.0, p < 0.05; sign test). The assistants made almost exclusively blue-yellow errors. The other color vision tests did not reveal any differences between the groups.
conclusionChanges in the retina are a possible explanation for the observed blue-yellow dyschromatopsia.
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