Observational studyEuropean radiology2019
Normative volume measurements of the fetal intra-cranial compartments using 3D volume in utero MR imaging.
Observational study in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Towards automated fetal brain biometry reporting for 3-dimensional T2-weighted 0.55-3T magnetic resonance imaging at 20-40 weeks gestational age range.Pediatric radiology · 2026Article
- Prenatal MRI features of fetal complete agenesis of the corpus callosum associated with unilateral hemispheric cortical malformation: a retrospective study.Frontiers in radiology · 2026Article
- In Utero MR Imaging for Fetuses with Small Head Sizes without Intracranial Abnormalities Detected on Ultrasonography.AJNR. American journal of neuroradiology · 2025Article
- Examining Craniofacial and Velopharyngeal Structures in Premature Infants: A Window Into the Womb.The Journal of craniofacial surgery · 2025Article
- Analysis of automatic fetal intracranial volume (ICV) measurement based on the optimized ultrasound Smart ICV method at 16-34 weeks of gestation.Quantitative imaging in medicine and surgery · 2024Article
- Fetal Brain Growth in the Early Second Trimester.AJNR. American journal of neuroradiology · 2023Observational
- Automatic biometry of fetal brain MRIs using deep and machine learning techniques.Scientific reports · 2023Article
- Sex differences in fetal intracranial volumes assessed by in utero MR imaging.Biology of sex differences · 2023Article
- Development of Gestational Age-Based Fetal Brain and Intracranial Volume Reference Norms Using Deep Learning.AJNR. American journal of neuroradiology · 2023Article
- Effective Approaches to Fetal Brain Segmentation in MRI and Gestational Age Estimation by Utilizing a Multiview Deep Inception Residual Network and Radiomics.Entropy (Basel, Switzerland) · 2022Article
- Article
- Clinical Applications of Fetal MRI in the Brain.Diagnostics (Basel, Switzerland) · 2022Review
- Quantification of Intracranial Structures Volume in Fetuses Using 3-D Volumetric MRI: Normal Values at 19 to 37 Weeks' Gestation.Frontiers in neuroscience · 2022Article
- Reference biometry of foetal brain by prenatal MRI and the distribution of measurements in foetuses with ventricular septal defect.Annals of medicine · 2021Article
- Single-Input Multi-Output U-Net for Automated 2D Foetal Brain Segmentation of MR Images.Journal of imaging · 2021Article
- An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset.Scientific data · 2021Article
- Ontogenetic and in silico models of spatial-packing in the hypermuscular mouse skull.Journal of anatomy · 2021Article
- Normative linear and volumetric biometric measurements of fetal brain development in magnetic resonance imaging.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Association of gestational age with MRI-based biometrics of brain development in fetuses.BMC medical imaging · 2020Article
- Normal appearances and dimensions of the foetal cavum septi pellucidi and vergae on in utero MR imaging.Neuroradiology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe the normal linear measurements of the skull (bi-parietal diameter and occipito-frontal diameter) and intracranial volumes (ventricular volume, brain parenchymal volume, extra-axial volume and total intra-cranial volume) in normal fetuses. MATERIALS AND
methodsWe recruited pregnant women from low-risk pregnancies whose fetuses had normal ultrasound and in utero MR studies. All volunteers had in utero MR imaging on the same 1.5T MR scanner with a protocol consisting of routine and 3D steady-state volume imaging of the fetal brain. Linear measurements of the skull were made using the volume imaging. The 3D volume imaging also was manually segmented to delineate the intracranial compartments described above to determine quantitative values for each.
resultsTwo hundred normal fetuses were studied with gestational ages between 18 and 37 weeks. The linear skull measurements made on in utero MR imaging closely correlate with published data from ultrasonography. The intracranial volume data is presented as graphs and as tabular summaries of 3rd, 10th, 50th, 90th and 97th centiles.
conclusionIt is now possible to measure the volumes of the intracranial compartments in individual fetuses using ultrafast in utero MR techniques. KEY POINTS: • There are limitations in using the skull size of the fetus to comment on the state of the fetal brain. • Volumes for the intracranial compartments are presented, based on in utero MR imaging of the fetal brain between 18 and 37 weeks gestational age. • Those normative values can be used to assess fetuses with known or suspected structural brain abnormalities and may assist the differential diagnosis provided by visual assessment of routine iuMR studies.
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