Evidence map›Paper›PMID 30683843›Full record

ArticleCell death & disease2019

SVIP alleviates CCl

Dan Jia, Yuan Yuan Wang, Pin Wang, Yao Huang, David Yuke Liang, Dongmei Wang, Chuandong Cheng, Caihua Zhang, Lianying Guo, Pin Liang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  6. Inhibiting Liver Autophagy and Promoting Hepatocyte Apoptosis byTropical medicine and infectious disease · 2024
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  10. [Exploring the effects of artesunate and fuzheng huayu decoction on mitochondria in the treatment of schistosomiasis liver fibrosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Dan JiaDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Yuan Yuan WangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Pin WangAdministration Department, Dalian Medical University, Dalian, China.
Yao HuangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
David Yuke LiangFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.
Dongmei WangDepartment of Experimental Functionality, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Chuandong ChengDepartment of Neurosurgery, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Hospital, Hefei, China.
Caihua ZhangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Lianying GuoDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Pin LiangThe First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yang WangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China. wang_yang10@aliyun.com.
Yujie JiaDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China. pathophy@163.com.
Cong LiDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China. goodluck_licong@163.com.
Dalian Medical University · CNUniversity of British Columbia · CAUniversity of Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged parenchymal cell death leads to activation of fibrogenic cells and extracellular matrix accumulation and eventually liver fibrosis. Autophagy, a major catabolic process of intracellular degradation and recycling, participates in hepatic fibrosis. However, the precise role of autophagy in the pathogenesis of hepatic fibrosis is controversial. The present study aims to investigate the key role of small VCP/p97 interacting protein (SVIP) against CCl

Indexed as

AutophagyAnimalsCarbon TetrachlorideCell SurvivalDisease Models, AnimalHepatocytesHep G2 CellsHumansLiver Cirrhosis, ExperimentalMembrane ProteinsMicePhosphate-Binding ProteinsRatsRats, Sprague-DawleyStarvationTransfectionCarbon TetrachlorideMembrane ProteinsPhosphate-Binding ProteinsSVIP protein, human

Identifiers

PMID30683843
PMCPMC6347612
OpenAlexW2914436528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.