Evidence map›Paper›PMID 30683765›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019

Preclinical Evaluation of Benzazepine-Based PET Radioligands (

Achi Haider, Adrienne Müller Herde, Stefanie D Krämer, Jasmine Varisco, Claudia Keller, Katrin Frauenknecht, Yves P Auberson, Louisa Temme, Dina Robaa, Wolfgang Sippl and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Evaluation of (Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  4. Article
  5. Article
  6. Development and Validation of [Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  7. Comparison of three novel radiotracers for GluN2B-containing NMDA receptors in non-human primates:Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  8. First-in-Humans Brain PET Imaging of the GluN2B-ContainingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  9. Review
  10. NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  11. Article
  12. A Review of Molecular Imaging of Glutamate Receptors.Molecules (Basel, Switzerland) · 2020
    Review
  13. Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Achi HaiderInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Adrienne Müller HerdeInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Stefanie D KrämerInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Jasmine VariscoInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Claudia KellerInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Katrin FrauenknechtInstitute of Neuropathology, University of Zurich/University Hospital Zurich, Zurich, Switzerland.
Yves P AubersonNovartis Institutes for BioMedical Research, Basel, Switzerland.
Louisa TemmeInstitute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.
Dina RobaaInstitute of Pharmacy, Martin-Luther University of Halle-Wittenberg, Halle/Saale, Germany; and.
Wolfgang SipplInstitute of Pharmacy, Martin-Luther University of Halle-Wittenberg, Halle/Saale, Germany; and.
Roger SchibliInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Bernhard WünschInstitute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.
Linjing MuInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.
Simon M AmetameyInstitute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland simon.ametamey@pharma.ethz.ch.
ETH Zurich · CHUniversity Hospital of Zurich · CHMartin Luther University Halle-Wittenberg · DEUniversity of Münster · DENovartis (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aims to investigate the performance characteristics of the enantiomers of

Indexed as

Positron-Emission TomographyAnimalsBenzazepinesBrainBrain MappingHumansLigandsMaleRadiochemistryRadiopharmaceuticalsRatsRats, WistarReceptors, N-Methyl-D-AspartateReceptors, sigmaStereoisomerism(11)C-Me-NB1BenzazepinesLigandsNR2B NMDA receptorRadiopharmaceuticalsReceptors, N-Methyl-D-AspartateReceptors, sigmaGluN2BneurodegenerationPET imagingreceptor occupancyσ1-receptor

Identifiers

PMID30683765
PMCPMC6681693
OpenAlexW2913968632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.