Evidence map›Paper›PMID 30683710›Full record

Trial reportThe oncologist2019

Randomized Trial of a Tailored Cognitive-Behavioral Therapy Mobile Application for Anxiety in Patients with Incurable Cancer.

Joseph A Greer, Jamie Jacobs, Nicole Pensak, James J MacDonald, Charn-Xin Fuh, Giselle K Perez, Alina Ward, Colleen Tallen, Alona Muzikansky, Lara Traeger and 5 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The oncologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04735991 (A Real-world Clinical Study Evaluating the Quality of Life in Family Members of Colorectal Cancer Patients Based on a Whole Course Chronic Disease Management System for Cancer Patients' Family), which is not on this map. Cited by 49 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04735991 nasuspendednot on this mapstarted 2020, after this paper: background citation

A Real-world Clinical Study Evaluating the Quality of Life in Family Members of Colorectal Cancer Patients Based on a Whole Course Chronic Disease Management System for Cancer Patients' Family

TypeinterventionalSponsorChinese Academy of Medical SciencesRan2020 to 2022Enrolled100ConditionsQuality of LifeArmsKapok Initiative
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  4. Effect of applying digital health in palliative care for patients with advanced cancer: a meta-analysis and systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  9. The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  16. Predictors of initial engagement with an asynchronous cognitive behavioral stress management website among older women with nonmetastatic breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joseph A GreerMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA jgreer2@mgh.harvard.edu.
Jamie JacobsMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Nicole PensakUniversity of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
James J MacDonaldUniversity of California, Los Angeles, Los Angeles, California, USA.
Charn-Xin FuhMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Giselle K PerezMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Alina WardLee Memorial Health System, Fort Myers, Florida, USA.
Colleen TallenLee Memorial Health System, Fort Myers, Florida, USA.
Alona MuzikanskyMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Lara TraegerMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Frank J PenedoNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Areej El-JawahriMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
Steven A SafrenUniversity of Miami, Coral Gables, Florida, USA.
William F PirlHarvard Medical School, Boston, Massachusetts, USA.
Jennifer S TemelMassachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.

Funding

Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
NIDA NIH HHS K24 DA040489
6 · The paper itself

Abstract

backgroundThe aim of this study was to test the efficacy of a tailored cognitive-behavioral therapy (CBT) mobile application (app) to treat anxiety in patients with incurable cancer. MATERIALS AND

methodsPatients with incurable cancers (

resultsPatients (73.8% female; 91.0% white; mean age = 56.45 years, SD = 11.30) in both study groups reported improvements in anxiety, depression symptoms, and QOL from baseline to postassessment, with no significant differences in any outcome measure between groups. Secondary analyses showed that, among the subgroup of patients with severe baseline anxiety, those randomized to the CBT app had greater improvements on the HAM-A (Mean Difference = 7.44, standard error [SE] = 3.35,

conclusionBoth the tailored CBT app for anxiety and the health education program were associated with improvements in anxiety, mood, and QOL, but these outcomes did not differ between study groups. The CBT app was more beneficial than health education for patients with severe baseline anxiety. IMPLICATIONS FOR PRACTICE: A cognitive-behavioral therapy mobile application tailored to treat anxiety in patients with advanced cancer helps improve access to evidence-based supportive care in a convenient, private, and timely manner.

Indexed as

Mobile ApplicationsAgedAnxietyCognitive Behavioral TherapyFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedNeoplasmsNeoplasm StagingPalliative CarePatient Education as TopicPatient Health QuestionnaireQuality of LifeSeverity of Illness IndexAdvanced cancerAnxietyCognitive‐behavioral therapy

Identifiers

PMID30683710
PMCPMC6693695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.