Trial reportThe Journal of rheumatology1988
Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.
32 registry-linked trialsAbstract readClinical TrialRandomized Controlled Trial
In one paragraph
Trial report in The Journal of rheumatology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 32 registered trials, which are not on this map. Cited by 3,328 papers, 12 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
3,328citing papers in PubMed, 12 pooled it
3.3field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single and Repeated Leech Therapy for the Treatment of Late Stage Knee Osteoarthritis. A Randomized, Placebo Controlled Comparative Trial
Efficacy Evaluation of Intra-articular Hyaluronic Acid (Sinovial®) vs Synvisc® in the Treatment of Symptomatic Knee Osteoarthritis. A Double-blind, Controlled, Randomised, Parallel-group Non-inferiority Study
A Randomized, Placebo-Controlled Trial of Duloxetine Added to Nonsteroidal Anti-inflammatory Drugs in Patients With Knee Pain Due to Osteoarthritis Who Have Had Suboptimal Response to Nonsteroidal Anti-inflammatory Drug Treatment.
A Single Center, Randomized, Double-blind, Placebo-controlled 2-way Crossover Study to Investigate the Mechanism of Action of Etoricoxib in Subjects With Osteoarthritis Knee Pain.
Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement
Bipolar Versus Unipolar Intraarticular Pulsed Radiofrequency Thermocoagulation in Chronic Knee Pain Treatment: A Prospective Randomized Study
Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Unilateral Total Knee Arthroplasty --- A Randomized Controlled Trial
PARQVE - Project Arthritis Recovering Quality of Life by Means of Education - A Prospective Randomized Study Comparing the Educational Program With and Without Multidisciplinary Care
Inflammation Impact on Pain in Patients With Knee Osteoarthritis
The Effect of Mindfulness-Based Stress Reduction on Pain and Function in Persons With Knee Osteoarthritis
Clinical Evolution of Patients Suffering From Lower Limb Rheumatological Conditions 6 Months After Spa Treatment
Evaluation of the Added Value of an Educational Program Associated With a Conventional Spa Therapy of Knee Osteoarthritis Patients
Is Clinical Outcome of Robotic-Assisted TKA Better Than Conventional Manual TKA?Prospective, Randomized Study
Postoperative Rehabilitation After Knee Arthroplasty, With or Without Anti-Gravity Treadmill
Effect of Monazite Sands in Patients With Osteoarthritis of the Knee
Comparison of Efficacy of Biofeedback, Electrical Stimulation and Therapeutic Exercise in Patients With Knee Osteoarthritis
Molecular Pathways Involved in Knee Pain: an Observational Study
Effect of Hip Abductors Versus Knee Extensor Strengthening on Pain,Function and Quadriceps Isometric Strength in Knee Osteoarthritis
The Cost-effectiveness of Inpatient and Outpatient Physical Therapy Programs in Knee Osteoarthritis
NCT04931719 phase2 / phase3completednot on this mapstarted 2019, after this paper: background citation
Comparing Efficacy of Platelet-rich Plasma (PRP) Combined With Different Hyaluronan for the Treatment of Knee Osteoarthritis: a Randomized Control Trial
EN20-01: A 24 Week Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Moderate to Severe Knee Osteoarthritis Pain.
Patient Reported Outcomes in Lower Limb Reconstruction in a Clinical Context
Effects of Exercise-related Irisin on Inflammation and Pain in Individuals With Osteoarthritis
Auburn University Joint Health Study
Evaluation of the Effectiveness of a Phlebology-oriented Spa Treatment on the Quality of Life of Patients Suffering from Chronic Venous Insufficiency of the Lower Limbs, 6-month After the Spa Treatment
Use of Leukocyte-Rich PRP or Leukocyte-Free PRP in the Treatment of Hip Osteoarthritis. Double-blind Controlled Randomized Clinical Trial
The Effect of St. John's Wort Oil on Pain Intensity and Physical Functions in People With Knee Osteoarthritis: a Qualitative and Randomized Placebo-controlled Trial
A Digital Mindset Intervention to Improve Pain and Exercise Participation in Individuals With Knee Osteoarthritis: A Randomized, Parallel-group Study
Continuous Radiofrequency in Hip Osteoarthritis Pain: A Protocol of a Randomized Clinical Trial
Efficacy of Therapy With Intra-articular Injections of PRP Compared With Therapy With Intra-articular Injections of HA, in Patients With Grade III or IV GONArthrosis: a Prospective Randomized Open-label Study
Efficacy of Shock Wave Treatment to Reduce Pain and Improve Functionality in Patients With Knee Osteoarthritis: Randomized Clinical Trial.
NCT07395427 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation
Comparison of the Effects of Basic Body Awareness Therapy to Conventional Physiotherapy and Home Exercise Program in Individuals With Knee Osteoarthritis
Who cites it
3,328 citing papers in PubMed, 12 syntheses or guidelines pooled it, 7,819 citations in OpenAlex.
- Feasibility and outcomes of the direct anterior approach in total hip arthroplasty for obese patients: a systematic review.Musculoskeletal surgery · 2026Pooled it
- Minimal clinically important difference (MCID), patient-acceptable state (PASS), minimally detectable change (MDC), and substantial clinical benefit (SCB) in patients who have undergone arthroscopic surgery for femoroacetabular impingement: a systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Pooled it
- Are preoperative psychological factors associated with chronic postoperative pain after total knee arthroplasty: a systematic review.EFORT open reviews · 2026Pooled it
- Hydrotherapy in the Rehabilitation of Functional Performance and Gait in Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Safety and efficacy of robot-assisted total knee arthroplasty: a network meta-analysis and systematic review.Journal of orthopaedic surgery and research · 2026Pooled it
- Factors Contributing to Variability in Longitudinal Pain Scores in Osteoarthritis Randomised Clinical Trials: A Systematic Review and Meta-Analysis.European journal of pain (London, England) · 2026Pooled it
- Autologous platelet-rich plasma versus hyaluronic acid, corticosteroids or saline for knee osteoarthritis: can blood draw volume serve as a proxy for platelet dose? A systematic review and meta-analysis.International orthopaedics · 2026Pooled it
- Leukocyte-rich versus leukocyte-poor platelet-rich plasma and hyaluronic acid for knee osteoarthritis: a systematic review and network meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Evaluating methodological quality of prognostic prediction models on patient-reported outcome measurements after total hip and total knee arthroplasty : a systematic review.Bone & joint open · 2026Pooled it
- Comparative analysis of surgical approaches in total hip arthroplasty: a systematic review of comparative outcomes including primary and revision cases.Journal of orthopaedic surgery and research · 2026Pooled it
- Clinical relevance of patient-reported outcome measures in the surgical management of focal chondral defects of the knee: a systematic review.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Pooled it
- Optimal resistance training strategies for knee osteoarthritis symptom relief: a systematic review and network meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Minimal Important Change and Minimal Clinically Important Difference in Pain and Function With Exercise in Hip Osteoarthritis.Arthritis care & research · 2026Trial
- Genicular Artery Embolization Using Imipenem/Cilastatin vs. Microsphere for Knee Osteoarthritis (GAUCHO). 12-Month Clinical Results of a Single-blind Randomized Controlled Trial.Cardiovascular and interventional radiology · 2026Trial
- Does Long-Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?Arthritis care & research · 2026Trial
- Trial
- Intra-articular platelet-rich plasma demonstrates superior clinical and serum biomarker outcomes compared with corticosteroids and NSAIDs in late-stage knee osteoarthritis: a randomised controlled trial.Journal of orthopaedic surgery and research · 2026Trial
- Cognitive muscular therapy™ for knee osteoarthritis: A feasibility randomised controlled trial.Osteoarthritis and cartilage open · 2026Trial
- Efficacy of the use of 3D printing models in the treatment of tibial plateau fractures: a pilot randomized clinical trial.Journal of orthopaedic surgery and research · 2026Trial
- GABRB3 Gene Polymorphisms Influences the Analgesic Response to Acupuncture Treatment in Patients With Chronic Knee Pain: A Randomized Controlled Neuroimaging Transcriptomics Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Trial
3,268 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors at 2 institutions in 1 country.
N BellamyUniversity of Western Ontario, London, Canada.
W W Buchanan
C H Goldsmith
J Campbell
L W Stitt
Western University · CAMcMaster University · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
Within the context of a double blind randomized controlled parallel trial of 2 nonsteroidal antiinflammatory drugs, we validated WOMAC, a new multidimensional, self-administered health status instrument for patients with osteoarthritis of the hip or knee. The pain, stiffness and physical function subscales fulfil conventional criteria for face, content and construct validity, reliability, responsiveness and relative efficiency. WOMAC is a disease-specific purpose built high performance instrument for evaluative research in osteoarthritis clinical trials.
Indexed as
Health Status IndicatorsHealth SurveysHip JointKnee JointAgedAged, 80 and overClinical Trials as TopicConsumer BehaviorDouble-Blind MethodEvaluation Studies as TopicFemaleHumansMaleMiddle AgedOsteoarthritisPainisoxicamPiroxicam
Identifiers
PMID
3068365OpenAlex
W2274722622What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT00435773ClinicalTrials.gov
NCT00556608ClinicalTrials.gov
NCT01018680ClinicalTrials.gov
NCT01619150ClinicalTrials.gov
NCT01826305ClinicalTrials.gov
NCT02141529ClinicalTrials.gov
and 26 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.