Evidence map›Paper›PMID 30683285›Full record

ArticleJournal of pediatric nursing

Adverse Childhood Experiences and the Presence of Cancer Risk Factors in Adulthood: A Scoping Review of the Literature From 2005 to 2015.

Katie A Ports, Dawn M Holman, Angie S Guinn, Sanjana Pampati, Karen E Dyer, Melissa T Merrick, Natasha Buchanan Lunsford, Marilyn Metzler

Abstract readScoping Review
In one paragraph

Article in Journal of pediatric nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. The association between adverse childhood experiences and childhood obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
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  9. Health Associations of Positive Childhood Experiences: A Scoping Review of the Literature.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Katie A PortsDivision of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: kports@cdc.gov.
Dawn M HolmanDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: isc6@cdc.gov.
Angie S GuinnDivision of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: lsj8@cdc.gov.
Sanjana PampatiDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA. Electronic address: spampati@umich.edu.
Karen E DyerVirginia Commonwealth University, School of Medicine, Department of Health Behavior and Policy, Richmond, VA, USA. Electronic address: karen.dyer@va.gov.
Melissa T MerrickDivision of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: mmerrick@cdc.gov.
Natasha Buchanan LunsfordDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: igo3@cdc.gov.
Marilyn MetzlerDivision of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: mom7@cdc.gov.
Centers for Disease Control and Prevention · USUniversity of Michigan · USVirginia Commonwealth University · US

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
Training Program in Behavioral and Health Services Cancer Control ResearchR25CA093423 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI BROWN, RICHARD FREDERICK · 2002 to 2015
$2.9M
Intramural CDC HHS CC999999NCI NIH HHS R25 CA093423NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

Exposure to Adverse Childhood Experiences (ACEs) is associated with a host of harmful outcomes, including increased risk for cancer. A scoping review was conducted to gain a better understanding of how ACEs have been studied in association with risk factors for cancer. This review includes 155 quantitative, peer-reviewed articles published between 2005 and 2015 that examined associations between ACEs and modifiable cancer risk factors, including alcohol, environmental carcinogens, chronic inflammation, sex hormones, immunosuppression, infectious agents, obesity, radiation, ultraviolet (UV) radiation, and tobacco, among U.S. adults. This review highlights the growing body of research connecting ACEs to cancer risk factors, particularly alcohol, obesity, and tobacco. Fewer studies investigated the links between ACEs and chronic inflammation or infectious agents. No included publications investigated associations between ACEs and environmental carcinogens, hormones, immunosuppression, radiation, or ultraviolet radiation. Mitigating the impact of ACEs may provide innovative ways to effect comprehensive, upstream cancer prevention.

Indexed as

Life Change EventsAdultAdverse Childhood ExperiencesAge FactorsAlcohol DrinkingChildChild AbuseEnvironmental ExposureFemaleFollow-Up StudiesHumansIncidenceMaleNeoplasmsPediatric ObesityRisk AssessmentAdverse Childhood ExperiencesCancer preventionCancer riskChild abuse and neglect preventionScoping review

Identifiers

PMID30683285
PMCPMC6355255
OpenAlexW2899606891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.