Evidence map›Paper›PMID 30683265›Full record

ReviewObstetrics and gynecology clinics of North America2019

Germline and Somatic Tumor Testing in Gynecologic Cancer Care.

Jill Alldredge, Leslie Randall

Abstract readReview
In one paragraph

Review in Obstetrics and gynecology clinics of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Germline Testing for Patients WithJNCI cancer spectrum · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jill AlldredgeUniversity of California, Irvine, 333 The City Boulevard, Suite 1400, Orange, CA 92868, USA. Electronic address: jalldred@uci.edu.
Leslie RandallUniversity of California, Irvine, 333 The City Boulevard, Suite 1400, Orange, CA 92868, USA.

Funding

INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32CA060396 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BRISTOW, ROBERT EDWARD · 1994 to 2020
$4.6M
NCI NIH HHS T32 CA060396
6 · The paper itself

Abstract

New technologies have advanced the science of tumor biology and genomics. Commercially available germline and somatic testing modalities have the downstream benefits of enabling prevention strategies in women with hereditary cancers and their family members in addition to identifying women who benefit most from novel targeted therapeutics. The matrix of available testing is complex and evolving. Women's health providers need to be versed in benefits and limitations of available testing. Genetic counselors play a pivotal role in interpretation of relevant mutations, and in avoiding common pitfalls, but their skill set is not sufficient to optimally integrate cancer genomics into clinical practice.

Indexed as

Early Detection of CancerDNA Mutational AnalysisFemaleGenetic CounselingGenetic Predisposition to DiseaseGenetic TestingGenital Neoplasms, FemaleGerm-Line MutationHumansImmunohistochemistryGenomicsGermlineGynecologic cancerSomaticTumor testing

Identifiers

PMID30683265
PMCPMC7480763

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.