ReviewJournal of neuroengineering and rehabilitation2019
Transcranial direct current stimulation for the treatment of motor impairment following traumatic brain injury.
Review in Journal of neuroengineering and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The Role of Neuroinflammation in Shaping Neuroplasticity and Recovery Outcomes Following Traumatic Brain Injury: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Noninvasive electrical stimulation as a neuroprotective strategy in retinal diseases: a systematic review of preclinical studies.Journal of translational medicine · 2024Pooled it
- Effect of non-invasive brain stimulation on post-stroke cognitive impairment: a meta-analysis.Frontiers in neurology · 2024Pooled it
- Comparative efficacy and mechanistic insights of non-invasive neuromodulation and motor rehabilitation on functional reorganization of the supplementary motor area in subacute stroke: a narrative review.Frontiers in physiology · 2026Review
- Non-invasive brain stimulation: current and future applications in neurology.Nature reviews. Neurology · 2025Review
- Efficacy of Neurorehabilitation Approaches in Traumatic Brain Injury Patients: A Comprehensive Review.Life (Basel, Switzerland) · 2025Review
- Distinct Effects of Brain Activation Using tDCS and Observational Practice: Implications for Motor Rehabilitation.Brain sciences · 2024Article
- Investigation of Neuromodulatory Effect of Anodal Cerebellar Transcranial Direct Current Stimulation on the Primary Motor Cortex Using Functional Near-Infrared Spectroscopy.Cerebellum (London, England) · 2024Article
- Exploring the use of bimodal transcranial direct current stimulation to enhance movement in individuals with patellofemoral pain-A sham-controlled double blinded pilot study.Frontiers in human neuroscience · 2024Article
- Optimized high-definition tDCS in patients with skull defects and skull plates.Frontiers in human neuroscience · 2023Article
- A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation.Frontiers in human neuroscience · 2023Review
- MRI-Based Personalized Transcranial Direct Current Stimulation to Enhance the Upper Limb Function in Patients with Stroke: Study Protocol for a Double-Blind Randomized Controlled Trial.Brain sciences · 2022Article
- Intervention Effect of Non-Invasive Brain Stimulation on Cognitive Functions among People with Traumatic Brain Injury: A Systematic Review and Meta-Analysis.Brain sciences · 2021Review
- Transcranial Direct Current Stimulation as a Treatment Tool for Mild Traumatic Brain Injury.Brain sciences · 2021Review
- Predicting and Monitoring Upper-Limb Rehabilitation Outcomes Using Clinical and Wearable Sensor Data in Brain Injury Survivors.IEEE transactions on bio-medical engineering · 2021Article
- Brain stimulation in attention deficits after traumatic brain injury: a literature review and feasibility study.Pilot and feasibility studies · 2021Article
- Development and Application of Medicine-Engineering Integration in the Rehabilitation of Traumatic Brain Injury.BioMed research international · 2021Review
- Peering into the Brain through the Retrosplenial Cortex to Assess Cognitive Function of the Injured Brain.Neurotrauma reports · 2021Article
- Rehabilitation Treatment of Motor Dysfunction Patients Based on Deep Learning Brain-Computer Interface Technology.Frontiers in neuroscience · 2020Article
- Neurostimulation and Reach-to-Grasp Function Recovery Following Acquired Brain Injury: Insight From Pre-clinical Rodent Models and Human Applications.Frontiers in neurology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
After traumatic brain injury (TBI), motor impairment is less common than neurocognitive or behavioral problems. However, about 30% of TBI survivors have reported motor deficits limiting the activities of daily living or participation. After acute primary and secondary injuries, there are subsequent changes including increased GABA-mediated inhibition during the subacute stage and neuroplastic alterations that are adaptive or maladaptive during the chronic stage. Therefore, timely and appropriate neuromodulation by transcranial direct current stimulation (tDCS) may be beneficial to patients with TBI for neuroprotection or restoration of maladaptive changes.Technologically, combination of imaging-based modelling or simultaneous brain signal monitoring with tDCS could result in greater individualized optimal targeting allowing a more favorable neuroplasticity after TBI. Moreover, a combination of task-oriented training using virtual reality with tDCS can be considered as a potent tele-rehabilitation tool in the home setting, increasing the dose of rehabilitation and neuromodulation, resulting in better motor recovery.This review summarizes the pathophysiology and possible neuroplastic changes in TBI, as well as provides the general concepts and current evidence with respect to the applicability of tDCS in motor recovery. Through its endeavors, it aims to provide insights on further successful development and clinical application of tDCS in motor rehabilitation after TBI.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.