ArticleJournal of cardiothoracic surgery2019
Neurological complications after cardiac surgery: a retrospective case-control study of risk factors and outcome.
Article in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review.Frontiers in surgery · 2025Pooled it
- Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies.Medicina (Kaunas, Lithuania) · 2026Review
- Incidence and Factors Associated with Neurological Complications Following Pediatric Heart Surgery: A Retrospective Study.Journal of clinical medicine · 2026Article
- Article
- Association of Plasma BDNF Concentration and Val66Met Polymorphism with Postoperative Delirium After Cardiac Surgery Under General Anesthesia with Cardiopulmonary Bypass.Journal of clinical medicine · 2025Article
- Acute Ischemic Stroke Risk Following Cardiac Interventions in the United States From 2016 to 2021.Neurology · 2025Article
- The Efficacy of the Charlson Comorbidity Index and Its Age-Adjusted Version in Forecasting Mortality and Postoperative Outcomes Following Isolated Coronary Artery Bypass Grafting.Journal of clinical medicine · 2025Article
- Acute Ischemic and Hemorrhagic Cerebrovascular Strokes After Cardiac Surgery: Incidence, Predictors, and Outcomes.Critical care research and practice · 2025Article
- Preoperative Chest Computed Tomography Screening Reduces the Perioperative Stroke Rate in Patients at Risk of Aortic Calcification.Journal of personalized medicine · 2024Article
- Stroke after heart valve surgery: a single center institution report.Journal of cardiothoracic surgery · 2024Article
- Article
- Factors Associated with Early Mortality in Acute Type A Aortic Dissection-A Single-Centre Experience.Journal of clinical medicine · 2024Article
- Stroke after Cardiac Surgery: A Risk Factor Analysis of 580,117 Patients from UK National Adult Cardiac Surgical Audit Cohort.Journal of personalized medicine · 2024Article
- Original Article--Risk Factors for Neurological Complications and Short-term Outcomes After Pediatric Heart Surgery: A Retrospective Analysis.Journal of the Saudi Heart Association · 2024Article
- Critical Assessment of the Neurological Complications during High-Risk Anesthesia Procedures.Journal of surgery and research · 2024Article
- The Anti-Apoptotic Effect of Ranolazine on Cerebral Protection during Cardiopulmonary Bypass and Carotid Artery Surgery.Acta Cardiologica Sinica · 2024Article
- Neurological Complications Following Cardiac Surgery: Management and Future Directions.Galen medical journal · 2024Review
- Early Postoperative Neurologic Events Are Associated With Worse Outcome and Fatal Midterm Survival After Adult Heart Transplantation.Journal of the American Heart Association · 2023Article
- Risk Factors Associated with Ischemic Stroke in the Immediate Postoperative Period of Cardiac Surgery.Brazilian journal of cardiovascular surgery · 2023Article
- Cerebrovascular events after cardiovascular surgery: diagnosis, management and prevention strategies.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2023Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate incidence, risk factors, and outcomes of postoperative neurological complications in patients undergoing cardiac surgery.
methodsA total of 2121 patients underwent cardiac surgery between August, 2008 and December, 2013; 91/2121 (4.3%) underwent brain computed tomography (70/91, 77%) or magnetic resonance imaging (21/91, 23%) scan because of major stroke (37/2121, 1.7%) and a spectrum of transient neurological episodes as well as transient ischemic attacks and delirium /psychosis/seizures (54/2121, 2.5%). The mean age was 65.3 ± 12.1 years and 60 (65.9%) were male. Variables were compared among study- and matched-patients (n = 113) without neurological deficits.
resultsA total of 37/2121 (1.7%) patients had imaging evidence of stroke. Radiological examinations were done 5.72 ± 3.6 days after surgery. Patients with and without imaging evidence of stroke had longer intensive care unit length of stay (LOS) (13.8 ± 14.7 and 12.9 ± 15 days vs. 5.7 ± 12.1 days, respectively (p < 0.001) and hospital LOS (53 ± 72.8 and 35.5 ± 29.8 days vs. 18.4 ± 29.2 days, respectively (p < 0.001) than the control group. The hospital mortality of patients with and without imaging evidence of stroke was higher than the control group (7/37 patients [19%], and 12/54 patients [22%] vs. 4/115 patients [3%], respectively (p < 0.001). Multivariate analysis showed that bilateral internal carotid artery stenosis of any grade (p < .001), and re-do operations (p = .013) increased the risk of postoperative neurological complications.
conclusionsNeurological complications after cardiac surgery increase hospitalization and mortality even in patients without radiologic evidence of stroke. Bilateral internal carotid artery stenosis of any grade, suggesting a diffuse patient propensity toward atherosclerosis, and re-do operations increase the risk of postoperative neurological complications.
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