ArticleBMC veterinary research2019
Antibiotic treatment triggers gut dysbiosis and modulates metabolism in a chicken model of gastro-intestinal infection.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Timing of an antioxidant-acidifier feed additive modulates growth performance and cecal microbiota in broiler chickens during enrofloxacin exposure.Poultry science · 2026Article
- Surfactin from Bacillus subtilis 1-4 disrupts the cell membrane of zoonotic Staphylococcus intermedius in vitro and maintains gut microbiota community in urban pigeons.Gut pathogens · 2026Article
- Severity of Brachyspira hyodysenteriae colitis correlates to the changes observed in the microbiota composition and its associated functionality in the large intestine.Animal microbiome · 2025Article
- Effects of Cordyceps militaris solid medium on the growth performance, immunity parameters and intestinal health of broilers.Animal bioscience · 2025Article
- Florfenicol-induced dysbiosis impairs intestinal homeostasis and host immune system in laying hens.Journal of animal science and biotechnology · 2025Article
- Resistance to medically important antimicrobials in broiler and layer farms in Cameroon and its relation with biosecurity and antimicrobial use.Frontiers in microbiology · 2024Article
- Microbial Community and Abundance of Selected Antimicrobial Resistance Genes in Poultry Litter from Conventional and Antibiotic-Free Farms.Antibiotics (Basel, Switzerland) · 2023Article
- Exploring the Impact of the Gut Microbiome on Obesity and Weight Loss: A Review Article.Cureus · 2023Review
- Amoxicillin and thiamphenicol treatments may influence the co-selection of resistance genes in the chicken gut microbiota.Scientific reports · 2022Article
- Gut microbiota and age shape susceptibility to clostridial enteritis in lorikeets under human care.Animal microbiome · 2022Article
- Effect of Doxycycline Use in the Early Broiler Production Cycle on the Microbiome.Frontiers in microbiology · 2022Article
- Impact of Antibiotic Therapies on Resistance Genes Dynamic and Composition of the Animal Gut Microbiota.Animals : an open access journal from MDPI · 2021Review
- Feasibility of sodium long chain polyphosphate as a potential growth promoter in broilers.Journal of animal science and technology · 2021Article
- L. rhamnosus improves the immune response and tryptophan catabolism in laying hen pullets.Scientific reports · 2021Article
- Effects of prophylactic and therapeutic antimicrobial uses in small-scale chicken flocks.Zoonoses and public health · 2021Article
- 16S rRNA Sequencing Analysis of the Gut Microbiota in Broiler Chickens Prophylactically Administered with Antimicrobial Agents.Antibiotics (Basel, Switzerland) · 2021Article
- The complexities of the diet-microbiome relationship: advances and perspectives.Genome medicine · 2021Review
- Dietary supplementation with anti-IL-10 antibody during a severe Eimeria challenge in broiler chickens.Poultry science · 2020Article
- State-of-the-Art of the Nutritional Alternatives to the Use of Antibiotics in Humans and Monogastric Animals.Animals : an open access journal from MDPI · 2020Review
- The biological effects of microencapsulated organic acids and botanicals induces tissue-specific and dose-dependent changes to the Gallus gallus microbiota.BMC microbiology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfection of the digestive track by gastro-intestinal pathogens results in the development of symptoms ranging from mild diarrhea to more severe clinical signs such as dysentery, severe dehydration and potentially death. Although, antibiotics are efficient to tackle infections, they also trigger dysbiosis that has been suggested to result in variation in weight gain in animal production systems.
resultsHere is the first study demonstrating the metabolic impact of infection by a gastro-intestinal pathogen (Brachyspira pilosicoli) and its resolution by antibiotic treatment (tiamulin) on the host (chicken) systemic metabolism and gut microbiota composition using high-resolution
conclusionThis study indicates that infection and antibiotic treatment trigger dysbiosis that may impact host systemic energy metabolism and cause phenotypic and health modifications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.