Evidence map›Paper›PMID 30682695›Full record

ArticleJournal of affective disorders2019

Perinatal maternal depression in rural South Africa: Child outcomes over the first two years.

Joan Christodoulou, Karl Le Roux, Mark Tomlinson, Ingrid M Le Roux, Linnea Stansert Katzen, Mary Jane Rotheram-Borus

Erratum issuedAbstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  14. Costs of common perinatal mental health problems in South Africa.Global mental health (Cambridge, England) · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Joan ChristodoulouDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, 10920 Wilshire Blvd., Suite 350, Los Angeles, CA 90024, USA. Electronic address: CCHPublications@mednet.ucla.edu.
Karl Le RouxPrimary Health Care Directorate, University of Cape Town, Zithulele Hospital, P Bag X504, Mqanduli 5080, South Africa.
Mark TomlinsonDepartment of Psychology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.
Ingrid M Le RouxPhilani Maternal, Child Health and Nutrition Project, PO Box 40188, Elonwabeni, 7791 Cape Town, South Africa.
Linnea Stansert KatzenPhilani Maternal, Child Health and Nutrition Project, PO Box 40188, Elonwabeni, 7791 Cape Town, South Africa.
Mary Jane Rotheram-BorusDepartment of Psychiatry & Biobehavioral Sciences, Semel Institute, University of California, 10920 Wilshire Blvd., Suite 350, Los Angeles, CA 90024, USA. Electronic address: MRotheram@mednet.ucla.edu.
Neurobehavioral Systems · USStellenbosch University · ZAUniversity of Cape Town · ZA

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
An RCT to Improve the South African Government's Community Health Workers' Capacities to Deliver Evidence-based Interventions for Optimizing HIV Outcomes and Reducing its ComorbiditiesR01MH111391 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.8M
Post-doctoral HIV Research Training Program for HIV Combination PreventionT32MH109205 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.3M
NIMH NIH HHS P30 MH058107NIMH NIH HHS R01 MH111391NIMH NIH HHS T32 MH109205
6 · The paper itself

Abstract

aimsTo examine child outcomes over time among mothers with perinatally depressed mood in rural South Africa (SA).

methodsA representative sample of consecutive births (470/493) in the OR Tambo District of the Eastern Cape of South Africa (SA) were recruited and were reassessed at five points over the course of the next two years: 85% were reassessed at 3 months, 92% at 6 months, 88% at 9 months, 91% at 12 months, and 88% at 2 years post-birth. Over time, the children of mothers with perinatally depressed mood (16%) were compared to children of mothers without depressed mood using multiple linear and logistic regressions.

resultsMothers with perinatal depressed mood are significantly less likely to live with the child's father or their in-laws (23% vs 35%), have household incomes above 2000 ZAR (154 USD) (31% vs 51%), and significantly more likely to have experienced IPV prior (19% vs 9%) and during (32% vs 20%) pregnancy compared to mothers without depressed mood. There are no differences in age, education, primipara, HIV status (29% seropositive), or alcohol use. Growth and developmental delays and motor and speech milestones through 24 months post-birth are similar for mothers with and without perinatal depressed mood.

conclusionsDespite increased economic and partner difficulties associated with perinatal depressed mood, infant outcomes are similar in mothers with and without depressed mood in rural South Africa.

Indexed as

AdultAlcohol DrinkingChild, PreschoolDepressionFemaleHumansInfantLinear ModelsMaleMothersPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsRural PopulationSexual PartnersSouth AfricaChildrenDepressionFamiliesHealth outcomesLow and middle income countriesRural regionsSouth AfricaWomen

Identifiers

PMID30682695
PMCPMC6377283
OpenAlexW2910926601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.