Evidence map›Paper›PMID 30682453›Full record

ArticleThe Journal of allergy and clinical immunology2019

Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.

Neeta Thakur, Luisa N Borrell, Morgan Ye, Sam S Oh, Celeste Eng, Kelley Meade, Pedro C Avila, Harold J Farber, Denise Serebrisky, Emerita Brigino-Buenaventura and 7 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Socioeconomic status and acculturation as determinants of atopic disease prevalence in United States Latino children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Structural Racism and the Social Determinants of Health in Asthma.Advances in experimental medicine and biology · 2023
    Article
  8. Impact of caregiver depression on child asthma outcomes in Mexicans and Puerto Ricans.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  9. Acculturation and asthma in Asian American adults.The journal of allergy and clinical immunology. In practice · 2022
    Article
  10. Observational
  11. Latino-white disparities in ICD-coded asthma diagnosis among US children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  12. Structural racism and its pathways to asthma and atopic dermatitis.The Journal of allergy and clinical immunology · 2021
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 2 countries.

Neeta ThakurDepartment of Medicine, University of California, San Francisco, Calif. Electronic address: Neeta.Thakur@ucsf.edu.
Luisa N BorrellDepartment of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy, City University of New York, New York, NY.
Morgan YeDepartment of Medicine, University of California, San Francisco, Calif.
Sam S OhDepartment of Medicine, University of California, San Francisco, Calif.
Celeste EngDepartment of Medicine, University of California, San Francisco, Calif.
Kelley MeadeChildren's Hospital and Research Center Oakland, Oakland, Calif.
Pedro C AvilaAllergy ENT & Associates, Woodlands, Tex.
Harold J FarberDepartment of Pediatrics, Section of Pulmonology, Baylor College of Medicine and Texas Children's Hospital, Houston, Tex.
Denise SerebriskyPediatric Pulmonary Division, Jacobi Medical Center, Bronx, NY.
Emerita Brigino-BuenaventuraDepartment of Allergy and Immunology, Kaiser Permanente-Vallejo Medical Center, Vallejo, Calif.
William Rodriguez-CintronVeterans Caribbean Health Care System, San Juan, Puerto Rico.
Rajesh KumarAnn and Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.
Kirsten Bibbins-DomingoDepartment of Medicine, University of California, San Francisco, Calif.
Shannon ThyneDepartment of Pediatrics, University of California, Los Angeles, Calif.
Saunak SenDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tenn.
Jose R Rodriguez-SantanaCentro de Neumología Pediátrica, San Juan, Puerto Rico.
Esteban G BurchardDepartment of Medicine, University of California, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, Calif.
University of California, San Francisco · USCentro de Neumologia Pediatrica · PRCity University of New York · USENT and Allergy · USJacobi Medical Center · USKaiser Permanente Vallejo Medical Center · USLurie Children's Hospital · USTexas Children's Hospital · USUniversity of California, Los Angeles · USUniversity of Tennessee Health Science Center · USVA Caribbean Healthcare System · PR

Funding

ZOLENDRONIC ACID IN CHILDREN W/ SEVERE OSTEOGENESIS IMPERFECTAM01RR000188 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI PLON, SHARON E. · 1985 to 2011
$30.6M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
Transcriptomic and Pharmacogenetic Asthma Endotypes in Minority ChildrenR01HL135156 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A, ZIV, ELAD · 2017 to 2021
$4.1M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
UCSF Career Development Program in Omics of Lung DiseasesK12HL119997 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, ERLE, DAVID J · 2013 to 2017
$1.4M
Social adversities and asthma: a new phenotype?K23HL125551 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI THAKUR, NEETA · 2016 to 2020
$1.0M
Gene-Environment Analyses of Early Life Exposures and Asthma in Ethnically Diverse ChildrenR21ES024844 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, GAUDERMAN, WILLIAM JAMES · 2015 to 2017
$509k
NCRR NIH HHS M01 RR000188NHLBI NIH HHS K12 HL119997NHLBI NIH HHS K23 HL125551NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL128439NHLBI NIH HHS R01 HL135156NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIGMS NIH HHS T32 GM007546NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443
6 · The paper itself

Abstract

backgroundAcculturation is an important predictor of asthma in Latino youth, specifically Mexican Americans. Less is known about acculturation and pulmonary function measures.

objectiveWe sought to estimate the association of acculturation measures with asthma and pulmonary function in Latino youth and determine whether this association varies across Latino subgroups.

methodsWe included 1849 Latinos (302 Caribbean Spanish, 193 Central or South Americans, 1136 Mexican Americans, and 218 other Latino children) aged 8 to 21 years from 4 urban regions in the United States. Acculturation measures include nativity status, age of immigration, language of preference, and generation in the United States. We used multivariable logistic and linear regression models to quantify the association of acculturation factors with the presence of asthma (case-control study) and pulmonary function (case-only study), adjusting for demographic, socioenvironmental, and clinical variables.

resultsFor all acculturation measures (nativity status, age of immigration, language of preference, and generation in the United States), greater levels of acculturation were associated with greater odds of asthma. Among cases, high (English preference) and medium (equal preference for Spanish and English) levels of language acculturation were associated with decreased bronchodilator response compared with low (Spanish preference) levels (P = .009 and .02, respectively). Similarly, high language acculturation was associated with increased FEV

conclusionsAcculturation was associated with diagnosed asthma and pulmonary function in Latino children and is an important factor to consider in the management of Latino youth with asthma.

Indexed as

AcculturationHispanic or LatinoAdolescentAdultAsthmaCase-Control StudiesChildFemaleForced Expiratory VolumeHumansMaleYoung Adultacculturationasthmahealth disparitiesLatinopediatricsocial determinants of health

Identifiers

PMID30682453
PMCPMC9186509
OpenAlexW2912810595

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.