ArticlePloS one2019
Quantity and quality of image artifacts in optical coherence tomography angiography.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Optical Coherence Tomography Angiography Assessed Retinal and Choroidal Microvasculature Features in Patients with Retinitis Pigmentosa: A Meta-Analysis.BioMed research international · 2019Pooled it
- Correlation analysis of physical fitness and retinal microvasculature by OCT angiography in healthy adults.PloS one · 2019Trial
- Image Quality as an Important Confounder in Quantitative OCT Angiography: A Review with Quantitative Synthesis.Medical sciences (Basel, Switzerland) · 2026Review
- Prognostic value of expanded-field OCT angiography in visual acuity outcomes for non-proliferative diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Automated anatomically guided quality assessment for OCTA via multi-region analysis and statistical calibration.Biomedical optics express · 2026Article
- Instrument-integrated optical coherence tomography for quantitative assessment of tissue alteration in retinal endolaser photocoagulation.Biomedical optics express · 2026Article
- Effect of Optical Coherence Tomography Angiography Image Artifacts on Quantitation of Vessel Density and Perfusion.Ophthalmic surgery, lasers & imaging retina · 2026Article
- Extravascular Motion Signal Detected by OCT Angiography Indicates Altered Vascular-Tissue Biomechanical Interactions in Glaucoma.Investigative ophthalmology & visual science · 2026Article
- The AROMA Dataset for Automatic Detection of Artifact Type and Severity in Retinal Optical Coherence Tomography Angiography.Ophthalmic research · 2026Article
- The Artifacts in Macular and Peripapillary OCT Angiography in Patients with Different Severities of Glaucoma.Ophthalmology science · 2026Article
- Digital measurement of pupil size, corneal size, and eccentricity in Guinea pigs using python compared with traditional OCT.Scientific reports · 2025Article
- Optical coherence tomography angiography in neovascular age-related macular degeneration: comprehensive review of advancements and future perspective.Eye (London, England) · 2025Review
- Article
- Reduced Retinal Blood Vessel Densities Measured by Optical Coherence Tomography Angiography in Keratoconus Patients Are Negatively Correlated with Keratoconus Severity.Diagnostics (Basel, Switzerland) · 2024Article
- Optical Coherence Tomography Angiography as a Diagnostic Tool for Diabetic Retinopathy.Diagnostics (Basel, Switzerland) · 2024Review
- Enhancing foveal avascular zone analysis for Alzheimer's diagnosis with AI segmentation and machine learning using multiple radiomic features.Scientific reports · 2024Article
- Factors affecting optical coherence tomography angiography signal strength index in patients receiving intravitreal injection treatment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- The OSCAR-MP Consensus Criteria for Quality Assessment of Retinal Optical Coherence Tomography Angiography.Neurology(R) neuroimmunology & neuroinflammation · 2023Review
- Artificial Intelligence-Based Quantification of Central Macular Fluid Volume and VA Prediction for Diabetic Macular Edema Using OCT Images.Ophthalmology and therapy · 2023Article
- An Analysis of Optical Coherence Tomography Angiography (OCT-A) Perfusion Density Maps in Patients Treated for Retinal Vein Occlusion with Intravitreal Aflibercept.Diagnostics (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze quality and frequency of OCTA artifacts and to evaluate their impact on the interpretability of OCTA images.
design75 patients with diabetic retinopathy (DR), retinal artery occlusion (RAO), retinal vein occlusion (RVO), or neovascular age-related macular degeneration (nAMD) and healthy controls were enrolled in this cross-sectional study in the outpatient department of a tertiary eye care center.
methodsAll participants underwent an OCTA examination (spectral domain OCT Cirrus 5000 equipped with the AngioPlex module). OCTA scans were analyzed independently by two experienced ophthalmologists. Frequency of various artifacts for the entire OCTA scan and for different segmentation layers and the grading of OCTA interpretability were investigated.
resultsThe analysis of 75 eyes of 38 women and 37 men between 24 and 94 years were included. Six eyes had no retinal disease, 19 eyes had nAMD, 16 had DR, 19 eyes had RVO, and 15 eyes showed RAO. A macular edema (ME) was present in 40 of the diseased eyes. Projection artifacts occurred in all eyes in any structure below the superficial retinal vessel layer, segmentation and motion artifacts were found in 55% (41/75) and 49% (37/75) of eyes, respectively. Other artifacts occurred less frequently. Segmentation artifacts were significantly more frequent in diseased than in healthy eyes (p<0.01). Qualitative assessment of OCTA images was graded as excellent in 65% and sufficient in 25% of cases, adding up to 91% images deemed acceptable for examination. Presence of ME was associated with a significantly poorer interpretability (p<0.01). CONCLUSION AND RELEVANCE: Various artifacts appear at different frequencies in OCTA images. Nevertheless, a qualitative assessment of the OCTA images is almost always possible. Good knowledge of possible artifacts and critical analysis of the complete OCTA dataset are essential for correct clinical interpretation and determining a precise clinical diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.