Evidence map›Paper›PMID 30682045›Full record

ArticlePloS one2019

Cardiovascular magnetic resonance imaging feature tracking: Impact of training on observer performance and reproducibility.

Sören J Backhaus, Georg Metschies, Marcus Billing, Johannes T Kowallick, Roman J Gertz, Tomas Lapinskas, Burkert Pieske, Joachim Lotz, Boris Bigalke, Shelby Kutty and 4 more

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
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  15. Article
  16. Article
  17. Takotsubo Syndrome-Is There a Need for CMR?Current heart failure reports · 2021
    Review
  18. Review
  19. Article
  20. Defining the optimal temporal and spatial resolution for cardiovascular magnetic resonance imaging feature tracking.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sören J BackhausUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.
Georg MetschiesUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.
Marcus BillingUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.
Johannes T KowallickGerman Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.
Roman J GertzUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.
Tomas LapinskasGerman Heart Center Berlin (DHZB), University of Berlin, Department of Internal Medicine / Cardiology, Charité Campus Virchow Clinic, Berlin, Germany.
Burkert PieskeGerman Heart Center Berlin (DHZB), University of Berlin, Department of Internal Medicine / Cardiology, Charité Campus Virchow Clinic, Berlin, Germany.
Joachim LotzGerman Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.
Boris BigalkeCharité Campus Benjamin Franklin, University Medical Center Berlin, Department of Cardiology and Pneumology, Berlin, Germany.
Shelby KuttyChildren's Hospital and Medical Center, University of Nebraska College of Medicine, Omaha, United States of America.
Gerd HasenfußUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.
Philipp BeerbaumHanover Medical School, Department of Pediatric Cardiology and Intensive Care, Hanover, Germany.
Sebastian KelleGerman Heart Center Berlin (DHZB), University of Berlin, Department of Internal Medicine / Cardiology, Charité Campus Virchow Clinic, Berlin, Germany.
Andreas SchusterUniversity Medical Center Göttingen, Department of Cardiology and Pneumology, Georg-August University, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular magnetic resonance feature tracking (CMR-FT) is increasingly used for myocardial deformation assessment including ventricular strain, showing prognostic value beyond established risk markers if used in experienced centres. Little is known about the impact of appropriate training on CMR-FT performance. Consequently, this study aimed to evaluate the impact of training on observer variance using different commercially available CMR-FT software.

methodsIntra- and inter-observer reproducibility was assessed prior to and after dedicated one-hour observer training. Employed FT software included 3 different commercially available platforms (TomTec, Medis, Circle). Left (LV) and right (RV) ventricular global longitudinal as well as LV circumferential and radial strains (GLS, GCS and GRS) were studied in 12 heart failure patients and 12 healthy volunteers.

resultsTraining improved intra- and inter-observer reproducibility. GCS and LV GLS showed the highest reproducibility before (ICC >0.86 and >0.81) and after training (ICC >0.91 and >0.92). RV GLS and GRS were more susceptible to tracking inaccuracies and reproducibility was lower. Inter-observer reproducibility was lower than intra-observer reproducibility prior to training with more pronounced improvements after training. Before training, LV strain reproducibility was lower in healthy volunteers as compared to patients with no differences after training. Whilst LV strain reproducibility was sufficient within individual software solutions inter-software comparisons revealed considerable software related variance.

conclusionObserver experience is an important source of variance in CMR-FT derived strain assessment. Dedicated observer training significantly improves reproducibility with most profound benefits in states of high myocardial contractility and potential to facilitate widespread clinical implementation due to optimized robustness and diagnostic performance.

Indexed as

Image Interpretation, Computer-AssistedAdultAgedFemaleHealthy VolunteersHeart FailureHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle AgedMyocardial ContractionObserver VariationReproducibility of ResultsSoftwareVentricular Dysfunction

Identifiers

PMID30682045
PMCPMC6347155

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.