SynthesisCongenital heart disease2019
Safety of contraceptive use among women with congenital heart disease: A systematic review.
Synthesis in Congenital heart disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Reproductive journey in women with congenital heart disease: a systematic review of mental health implications.BMJ open · 2026Pooled it
- Cardiovascular Safety of Hormonal Contraception: Method-Specific Risks and Clinical Implications.Medical sciences (Basel, Switzerland) · 2026Review
- Comment on "Contraception Use in Adolescents and Young Adults with Congenital Heart Disease".Pediatric cardiology · 2025Article
- Navigating women with congenital heart disease during pregnancy: Management strategies and future directions.World journal of cardiology · 2025Review
- Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Endocarditis.Dentistry journal · 2025Review
- Pregnancy Considerations in Tetralogy of Fallot.CJC pediatric and congenital heart disease · 2023Review
- Review
- Reproductive Health Counseling and Concerns Among Women with Congenital Heart Defects With and Without Disabilities.Journal of women's health (2002) · 2023Article
- Reproductive Health of Women with Congenital Heart Defects.Journal of women's health (2002) · 2023Review
- Adolescent Women with Congenital Heart Disease: Self-Reported Reproductive Health Discussions with Health Care Providers.Journal of pediatric and adolescent gynecology · 2022Article
- Pregnancy in congenital heart disease: risk prediction and counselling.Heart (British Cardiac Society) · 2020Review
- Contraceptive methods of privately insured US women with congenital heart defects.American heart journal · 2020Article
- Creating a Multidisciplinary Pregnancy Heart Team.Current treatment options in cardiovascular medicine · 2020Review
- Adherence to clinical practice guidelines for South Australian pregnant women with cardiac conditions between 2003 and 2013.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveWomen with congenital heart disease (CHD) are at increased risk of pregnancy complications and need information on safe, effective contraceptive methods to avoid unintended pregnancy. This systematic review examines evidence regarding safety of contraceptive use among women with CHD.
methodsThe PubMed database was searched for any peer-reviewed articles published through April 2018 that included safety outcomes associated with reversible contraceptive methods among women with CHD.
resultsFive articles met inclusion criteria: three studies comparing contraceptive users to nonusers and two noncomparative studies. Sample sizes ranged from 65 to 505 women with CHD. Two studies found a higher percent of thromboembolic complications among women with Fontan palliation or transposition of the great arteries using oral contraceptives. One study, among women with Fontan palliation, found no increased risk of thromboembolic complications between contraceptive users (not separated by type) and nonusers. Two studies found no endocarditis among intrauterine device users.
conclusionsThere is a paucity of data regarding the safety of contraceptive methods among women with CHD. Limited evidence suggests an increased incidence of thromboembolic complications with use of oral contraceptives. Further studies are needed to evaluate contraceptive safety and quantify risk in this growing population. There is also limited data regarding the safety of contraceptive methods among women with CHD. Further information is needed to assist practitioners counseling women with CHD on safety of contraceptive methods.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.