ArticleMedicine2019
The association between ambient air pollution and birth defects in four cities in Hunan province, China, from 2014 to 2016.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 47 citations in OpenAlex.
- Prevalence and death rate of birth defects from population-based surveillance in Hunan Province, China, 2010-2020.Scientific reports · 2024Article
- Multivariate logistic regression analysis of risk factors for birth defects: a study from population-based surveillance data.BMC public health · 2024Article
- Examining modification of the associations between air pollution and birth outcomes by neighborhood deprivation in a North Carolina birth cohort, 2011-2015.Frontiers in reproductive health · 2024Article
- Update from a cohort study for birth defects in Hunan Province, China, 2010-2020.Scientific reports · 2023Article
- Perinatal Risks of Neonatal and Infant Mortalities in a Sub-provincial Region of China: A Livebirth Population-based Cohort Study.BMC pregnancy and childbirth · 2022Article
- Maternal Exposure to Sulfur Dioxide and Risk of Omphalocele in Liaoning Province, China: A Population-Based Case-Control Study.Frontiers in public health · 2022Article
- Understanding the Pathways from Prenatal and Post-Birth PMInternational journal of environmental research and public health · 2021Observational
- The association between ambient air pollution and birth defects in five major ethnic groups in Liuzhou, China.BMC pediatrics · 2021Article
- Maternal exposure to ambient SOEnvironmental science and pollution research international · 2021Article
- Maternal exposure to ambient levels of sulfur dioxide and risk of neural tube defects in 14 cities in Liaoning province, China: a population-based case-control study.Journal of exposure science & environmental epidemiology · 2021Article
- Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was performed to assess whether air pollution was positively associated with birth defects and if a specific pregnancy stage played a role. This was a population-based case-control study comprising 153,822 perinatal births in four cities located in Hunan province, China, during the period 2014 to 2016. Exposure to SO2, NO2, and PM10 in each pregnant woman in the first 3 months before pregnancy, and in the first and third trimester was assessed. The risk of birth defects related to SO2 in the first 3 months before pregnancy was between 1.191 and 1.566. In the first trimester stage the risk was between 1.104 and 1.348. The risk of birth defects related to NO2 before pregnancy was 1.285 (95%CI: 1.180-1.399), in the first trimester stage the risk was between 1.280 (95%CI: 1.197-1.368) and 1.380 (95%CI: 1.293-1.473). In the third month before delivery the risk was 1.484 (95%CI: 1.366-1.613). The risk of birth defects related to PM10 in the first month of pregnancy was 1.098 (95%CI: 1.057-1.140), and in the third month before delivery the risk was 1.296 (95%CI: 1.222-1.375). SO2 had a greater effect on the prophase of pregnancy, while NO2 and PM10 had an effect in the late third trimester.
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