Evidence map›Paper›PMID 30681429›Full record

ReviewJournal of orthopaedic trauma2019

Clinical Practice Guidelines for Pain Management in Acute Musculoskeletal Injury.

Joseph R Hsu, Hassan Mir, Meghan K Wally, Rachel B Seymour, Orthopaedic Trauma Association Musculoskeletal Pain Task Force

3 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Journal of orthopaedic trauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 115 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 5 pooled it
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03671746 phase1completednot on this map

Inflammatory Response to Trauma - Does Early Cytokine Modulation Improve Patient Outcome

TypeinterventionalSponsorArun AnejaRan2019 to 2023Enrolled70ConditionsPolytraumaArmsKetorolac, Saline Solution
NCT04555239 naterminatednot on this mapstarted 2020, after this paper: background citation

Treatment of Subacute and Chronic Extremity Pain With Fascial Distortion Model (FDM) in the Emergency Department

TypeinterventionalSponsorCarilion ClinicRan2020 to 2022Enrolled19ConditionsMyofascial Pain, Chronic Pain, Extremities Disorders, Osteopathic ManipulationArmsFascial Distortion Model (FDM), Standard Care
NCT05391464 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Preoperative Versus Postoperative Peripheral Nerve Block for Pain Control After Ankle and Wrist Fracture Surgery

TypeinterventionalSponsorMaineGeneral HealthRan2022 to 2025Enrolled160ConditionsAnkle Fractures, Distal Radius FractureArmsPeripheral Nerve Block
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 5 syntheses or guidelines pooled it, 256 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Pooled it
  5. Pooled it
  6. Trial
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  9. Postoperative Intravenous Ketorolac Does Not Affect Nonunion Risk in Surgically Treated Long Bone Shaft Fractures.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Perioperative Ketorolac Is Associated With Lower Mortality After Surgically Treated Hip Fracture in Older Adults.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  15. Pain Management Strategies in Reverse Total Shoulder Arthroplasty.Current reviews in musculoskeletal medicine · 2026
    Review
  16. Article
  17. Clinical impact of acute symptomatic vertebral fractures in the United States: A patient survey and chart review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  18. Article
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph R HsuDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, NC.
Hassan MirFlorida Orthopaedic Institute, University of South Florida, Tampa, FL.
Meghan K WallyDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, NC.
Rachel B SeymourDepartment of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, NC.
Orthopaedic Trauma Association Musculoskeletal Pain Task Force
OrthoCarolina · USUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to produce comprehensive guidelines and recommendations that can be utilized by orthopaedic practices as well as other specialties to improve the management of acute pain following musculoskeletal injury.

methodsA panel of 15 members with expertise in orthopaedic trauma, pain management, or both was convened to review the literature and develop recommendations on acute musculoskeletal pain management. The methods described by the Grading of Recommendations Assessment, Development, and Evaluation Working Group were applied to each recommendation. The guideline was submitted to the Orthopaedic Trauma Association (OTA) for review and was approved on October 16, 2018.

resultsWe present evidence-based best practice recommendations and pain medication recommendations with the hope that they can be utilized by orthopaedic practices as well as other specialties to improve the management of acute pain following musculoskeletal injury. Recommendations are presented regarding pain management, cognitive strategies, physical strategies, strategies for patients on long term opioids at presentation, and system implementation strategies. We recommend the use of multimodal analgesia, prescribing the lowest effective immediate-release opioid for the shortest period possible, and considering regional anesthesia. We also recommend connecting patients to psychosocial interventions as indicated and considering anxiety reduction strategies such as aromatherapy. Finally, we also recommend physical strategies including ice, elevation, and transcutaneous electrical stimulation. Prescribing for patients on long term opioids at presentation should be limited to one prescriber. Both pain and sedation should be assessed regularly for inpatients with short, validated tools. Finally, the group supports querying the relevant regional and state prescription drug monitoring program, development of clinical decision support, opioid education efforts for prescribers and patients, and implementing a department or organization pain medication prescribing strategy or policy.

conclusionsBalancing comfort and patient safety following acute musculoskeletal injury is possible when utilizing a true multimodal approach including cognitive, physical, and pharmaceutical strategies. In this guideline, we attempt to provide practical, evidence-based guidance for clinicians in both the operative and non-operative settings to address acute pain from musculoskeletal injury. We also organized and graded the evidence to both support recommendations and identify gap areas for future research.

Indexed as

Practice Guidelines as TopicHumansMusculoskeletal PainMusculoskeletal SystemPain ManagementWounds and Injuries

Identifiers

PMID30681429
PMCPMC6485308
OpenAlexW2913714595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.