ArticleJournal of the American Heart Association2019
Carotid Artery Echolucency, Texture Features, and Incident Cardiovascular Disease Events: The MESA Study.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Grayscale Ultrasound Texture Features of Carotid and Brachial Arteries in People With HIV Infection Before and After Antiretroviral Therapy.Journal of the American Heart Association · 2022Trial
- Comparison of 2D and 3D carotid plaque analysis and longitudinalJournal of medical imaging (Bellingham, Wash.) · 2026Article
- Future of Families: Cardiovascular Health Among Young Adults Cohort Study: Rationale, Key Questions, Study Design, and Participant Characteristics.Journal of the American Heart Association · 2025Article
- Comparative Analysis of Common Carotid Artery Intima-Media Thickness and Lagrangian Wall Strain in Relation to Cardiovascular Risk Factors Using Ultrasound.Ultrasound in medicine & biology · 2025Article
- Linking the Planetary Health Diet Index to sarcopenia: the mediating effect of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR).Frontiers in nutrition · 2025Article
- Carotid Artery Wall Echogenicity Measured by Gray Scale Median of the Intima-Media Complex From Childhood to Young Adulthood.Journal of the American Heart Association · 2024Article
- Amyloid beta is associated with carotid wall echolucency and atherosclerotic plaque composition.Scientific reports · 2024Article
- Determinants of Carotid Wall Echolucency in a Cohort of European High Cardiovascular Risk Subjects: A Cross-Sectional Analysis of IMPROVE Baseline Data.Biomedicines · 2024Article
- A clinical-radiomics combined model based on carotid atherosclerotic plaque for prediction of ischemic stroke.Frontiers in neurology · 2024Article
- Pregnancy as an Early Cardiovascular Moment: Peripartum Cardiovascular Health.Circulation research · 2023Review
- Carotid wall echogenicity at baseline associates with accelerated vascular aging in a middle-aged population.The international journal of cardiovascular imaging · 2023Article
- Imaging and Hemodynamic Characteristics of Vulnerable Carotid Plaques and Artificial Intelligence Applications in Plaque Classification and Segmentation.Brain sciences · 2023Review
- Changes in carotid artery texture by ultrasound and elastin features in a murine model.Frontiers in cardiovascular medicine · 2023Article
- Carotid Artery Stiffness Mechanisms in Hypertension and Their Association with Echolucency and Texture Features: The Multi-ethnic Study of Atherosclerosis (MESA).Ultrasound in medicine & biology · 2022Article
- Protocol of Aerobic Exercise and Cognitive Health (REACH): A Pilot Study.Journal of Alzheimer's disease reports · 2020Article
- Carotid and Femoral Atherosclerotic Plaques in Asymptomatic and Non-Treated Subjects: Cardiovascular Risk Factors, 10-Years Risk Scores, and Lipid Ratios´ Capability to Detect Plaque Presence, Burden, Fibro-Lipid Composition and Geometry.Journal of cardiovascular development and disease · 2020Article
- Cardiovascular disease risk and pathophysiology in South Asians: can longitudinal multi-omics shed light?Wellcome open research · 2020Review
- Changes in carotid artery structure with smoking cessation.Vascular medicine (London, England) · 2019Article
- Carotid Artery Echolucency, Texture Features, and Incident Cardiovascular Disease Events: The MESA Study.Journal of the American Heart Association · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Background We hypothesized that measures of common carotid artery echolucency and grayscale texture features were associated with cardiovascular disease ( CVD ) risk factors and could predict CVD events. Methods and Results Using a case-cohort design, we measured common carotid artery ultrasound images from 1788 participants in Exam 1 of the MESA study (Multi-Ethnic Study of Atherosclerosis) to derive 4 grayscale features: grayscale median, entropy, gray level difference statistic-contrast, and spatial gray level dependence matrices-angular second moment. CVD risk factor associations were determined by linear regression. Cox proportional hazard models with inverse selection probability weighting and adjustments for age, sex, race/ethnicity, CVD risk factors, and C-reactive protein were used to determine if standardized values for grayscale median, entropy, gray level difference statistic-contrast, and spatial gray level dependence matrices-angular second moment could predict incident coronary heart disease, stroke, and total CVD events over a median 13 years follow-up. Participants were mean ( SD ) 63.1 (10.3) years of age, 52.6% female, 32.1% white, 27.8% black, 23.3% Hispanic, and 16.8% Chinese. There were 283 coronary heart disease, 120 stroke, and 416 CVD events. Several associations of grayscale features with CVD risk factors were identified. In fully adjusted models, higher gray level difference statistic-contrast was associated with a lower risk of incident coronary heart disease (hazard ratio 0.82, 95% CI 0.71-0.94, p
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