Observational studyEuropean journal of preventive cardiology2019
The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension (African-PREDICT): Design, recruitment and initial examination.
Observational study in European journal of preventive cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can postexercise hypotension also be observed in African and Asian populations: a systematic review and meta-analysis of randomized controlled trials.Journal of human hypertension · 2023Pooled it
- Phenotyping Kidney Function in Young Adults With High Blood Pressure: The African-PREDICT Study.Journal of clinical hypertension (Greenwich, Conn.) · 2024Trial
- Fibrosis-4 index and cardiac remodelling in the general population: The STANISLAS and African-PREDICT cohorts.American journal of preventive cardiology · 2026Article
- Potassium intake assessed by dietary recall and urinary excretion in young South African adults: findings from the African-PREDICT study.BMC public health · 2026Article
- When the sum isn't the whole - The vascular status score and its components in hypertension identification: The African PREDICT study.Journal of human hypertension · 2026Article
- Response to Correspondence: From single risks to causal pathways: future directions for early cardiovascular biomarker research.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Associations between pulse pressure amplification and inflammation in young adults according to body composition: The African-PREDICT study.Journal of human hypertension · 2026Article
- Angiotensinogen and its relationship with blood pressure in young adults: the African-PREDICT study.Journal of human hypertension · 2026Article
- Cross-Sectional and Longitudinal Associations Between Dietary Intake and Depressive Symptoms in Young South African Adults: The African-PREDICT Study.Depression and anxiety · 2026Observational
- Evaluation of race-free eGFR equations in individuals of different ethnicity.Blood pressure · 2025Article
- Profiling endothelial function, oxidative stress and inflammatory biomarkers in individuals with various cardiovascular risk factors: the African-PREDICT study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Hypertension Criteria and the Early Detection of Vascular Aging in Youth.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- The relationship between kidney function and the soluble (pro)renin receptor in young adults: the African-PREDICT study.BMC nephrology · 2025Article
- Estimating the Burden of Common Mental Disorders Attributable to Lifestyle Factors: Protocol for the Global Burden of Disease Lifestyle and Mental Disorder (GLAD) Project.JMIR research protocols · 2025Article
- Hypertension in sub-Saharan Africa: the current profile, recent advances, gaps, and priorities.Journal of human hypertension · 2025Review
- Machine learning model for detecting masked hypertension in young adults.Frontiers in physiology · 2025Article
- Article
- Nutrient intake of young South African adults from the baseline of the African-PREDICT cohort study.Public health nutrition · 2024Article
- Amino acid profiles associated with plant-rich protein diets may contribute to lower blood pressure.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Urinary metabolomics signature of animal and plant protein intake and its association with 24-h blood pressure: the African-PREDICT study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
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23 authors.
Funding
Abstract
backgroundGlobally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be attributed to poor healthcare and ineffective antihypertensive treatment, there is a limited understanding of population and individual-specific cardiovascular pathophysiology - necessary for effective prevention and treatment strategies in Africa. As there is a lack of longitudinal studies tracking the early pathophysiological development of hypertension in black populations, the African-PREDICT study was initiated. The purpose of this paper is to describe the detailed methodology and baseline cohort profile of the study. METHODS AND
resultsFrom 2013 to 2017, the study included 1202 black ( N = 606) and white ( N = 596) men and women (aged 20-30 years) from South Africa - screened to be healthy and clinic normotensive. At baseline, and each 5-year follow-up examination, detailed measures of health behaviours, cardiovascular profile and organ damage are taken. Also, comprehensive biological sampling for the 'omics' and biomarkers is performed. Overall, the baseline black and white cohort presented with similar ages, clinic and 24-hour blood pressures, but black adults had lower socioeconomic status and higher central systolic blood pressure than white individuals.
conclusionsThe prospective African-PREDICT study in young black and white adults will contribute to a clear understanding of early cardiovascular disease development.
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