Observational studyJournal of cachexia, sarcopenia and muscle2019
Body weight changes and incidence of cachexia after stroke.
Observational study in Journal of cachexia, sarcopenia and muscle, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 48 citations in OpenAlex.
- Influence of CReatine Supplementation on mUScle Mass and Strength After Stroke (ICaRUS Stroke Trial): A Randomized Controlled Trial.Nutrients · 2024Trial
- Targeting Neuroinflammation in the Piriform Cortex-Amygdala: Enhanced Efficacy of Niosome-Based Sodium Butyrate in Ischemic Stroke.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026Article
- The association of post-stroke changes in body mass index with activity of daily living and instrumental activity of daily living trajectories: A multi-cohort analysis.The journal of nutrition, health & aging · 2026Article
- Combined nutritional and inflammatory risk stratification for predicting functional outcomes in acute ischemic stroke.Frontiers in nutrition · 2026Article
- Efficacy of an evidence-based telehealth-delivered weight-loss intervention to expand reach and enhance access to underserved groups after stroke.Contemporary clinical trials communications · 2025Article
- Comparison of changes in skeletal muscle mass after stroke categorized by the severity of motor dysfunction: a retrospective study.Journal of physical therapy science · 2025Article
- Neural Circuits Underlying Reciprocal Cardiometabolic Crosstalk: 2023 Arthur C. Corcoran Memorial Lecture.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice.ACS pharmacology & translational science · 2024Article
- Cross-sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study.Journal of cachexia, sarcopenia and muscle · 2024Article
- Association between abdominal adiposity and clinical outcomes in patients with acute ischemic stroke.PloS one · 2024Article
- Recombinant Human Perlecan DV and Its LG3 Subdomain Are Neuroprotective and Acutely Functionally Restorative in Severe Experimental Ischemic Stroke.Translational stroke research · 2023Article
- Beneficial effects of buspirone in endothelin-1 induced stroke cachexia in rats.Molecular and cellular biochemistry · 2023Article
- Effects of body mass index on the immune response within the first days after major stroke in humans.Neurological research and practice · 2023Article
- Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Impact of a Rehabilitation Program on the Change in Components of Body Mass of the Upper and Lower Limbs in People After Ischemic Stroke.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Iron deficiency is related to low functional outcome in patients at early rehabilitation after acute stroke.Journal of cachexia, sarcopenia and muscle · 2022Observational
- Effects of Artificial Intelligence-Derived Body Composition on Kidney Graft and Patient Survival in the Eurotransplant Senior Program.Biomedicines · 2022Article
- Artificial intelligence-based analysis of body composition in Marfan: skeletal muscle density and psoas muscle index predict aortic enlargement.Journal of cachexia, sarcopenia and muscle · 2021Article
- Risk of Weight Loss in Adult Patients and the Effect of Staffing Registered Dietitians in Kaifukuki (Convalescent) Rehabilitation Wards: A Retrospective Analysis of a Nationwide Survey.Healthcare (Basel, Switzerland) · 2021Article
- Are Sarcopenia and Cognitive Dysfunction Comorbid after Stroke in the Context of Brain-Muscle Crosstalk?Biomedicines · 2021Review
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBody weight loss is a frequent complication after stroke, and its adverse effect on clinical outcome has been shown in several clinical trials. The purpose of this prospective longitudinal single-centre observational study was to investigate dynamical changes of body composition and body weight after ischemic stroke and an association with functional outcome.
methodsSixty-seven consecutive patients (age 69 ± 11 years, body mass index 27.0 ± 4.1 kg/m
resultsAccording to the body weight changes after 12 months, 42 (63%) patients had weight gain or stable weight, 11 (16%) patients had moderate weight loss, and 14 (21%) patients became cachectic. A relative decline of 19% of fat tissue and 6.5% of lean tissue was observed in cachectic patients, while no changes of lean tissue were observed in non-cachectic patients after 12 months. The modified Rankin Scale was 48% higher (2.1 ± 1.6, P < 0.05), Barthel Index was 22% lower (71 ± 39, P < 0.01), and handgrip strength was 34% lower (21.9 ± 13.0, P < 0.05) in cachectic compared to non-cachectic patients after 12 months. The low physical performance if defined by Barthel Index <60 points was linked to the lean tissue wasting (OR 44.8, P < 0.01), presence of cachexia (OR 20.8, P < 0.01), and low body mass index <25 kg/m
conclusionsIn this cohort study, every fifth patient with ischemic stroke fulfilled the criteria of cachexia within 12 months after index event. The incidence of cachexia was 21%. Cachectic patients showed the lowest functional and physical capacity.
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