Evidence map›Paper›PMID 30680678›Full record

ReviewDrugs & aging2019

Practical Regional Anesthesia Guide for Elderly Patients.

Carole Lin, Curtis Darling, Ban C H Tsui

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drugs & aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Lifetime Pain Management Experiences of Female Breast Cancer Survivors Aged 65+ Years.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Older Women and Opioid Analgesia after Breast Cancer Surgery.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Article
  11. Article
  12. Perioperative Pulmonary Support of the Elderly.Current geriatrics reports · 2021
    Review
  13. Review
  14. Anesthetic management of geriatric patients.Korean journal of anesthesiology · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carole LinDepartment of Anesthesiology, Perioperative and Pain Medicine, Lucille Packard Children's Hospital, Stanford University, School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA.
Curtis DarlingDepartment of Anesthesiology, Perioperative and Pain Medicine, Lucille Packard Children's Hospital, Stanford University, School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA.
Ban C H TsuiDepartment of Anesthesiology, Perioperative and Pain Medicine, Lucille Packard Children's Hospital, Stanford University, School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA. bantsui@stanford.edu.ORCID 0000-0002-6984-5998
Lucile Packard Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound-guided regional anesthesia is an important part of the practice of anesthesia for the elderly population, the growth of which will continue to outpace that of the younger population due to improvements in lifespan worldwide. The elderly patient is uniquely vulnerable to the effects of systemic anesthetic drugs, and our understanding of the potential toxicities that general anesthetics can have on the elderly brain and body continues to evolve. Aging impacts both the pharmacokinetics and pharmacodynamics of sedative medications and local anesthetics. Alongside the physiologic aging process often comes a myriad of pathologic co-morbidities that can accumulate with age, and result in a great variability of physiologic reserve. This variability in overall functional status is described by a newer concept termed 'frailty,' which is used to evaluate and risk-stratify elderly patients perioperatively. The choice for regional anesthesia is based on a combination of factors such as duration of surgery, pre-existing patient risk factors, and the skill and technique of the anesthesiologist. The utilization of preoperative and intraoperative sedation is now recognized as a key component in maximizing the safety and success rate of regional anesthesia. Excellent pain management with minimal to no sedation during the operation may have benefits that extend far beyond the immediate perioperative setting. Regional anesthesia is increasingly integrated as an important part of multimodal enhanced recovery after surgery (ERAS) protocols, which aim to decrease the cost, enhance safety, and improve the patient's subjective experience during and after hospitalization. Ultrasound-guided techniques, recently developed regional blocks, medications for sedation, and local anesthetics are reviewed in this article.

Indexed as

AgedAge FactorsAnesthesia, ConductionAnestheticsGeriatric AssessmentGeriatricsHumansRandomized Controlled Trials as TopicUltrasonographyAnesthetics

Identifiers

PMID30680678
OpenAlexW2914324482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.