ArticleJapanese journal of radiology2019
Differences in gross tumor volumes for pancreatic cancer: a comparison of ungated positron emission tomography and contrast-enhanced four-dimensional computed tomography.
Article in Japanese journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeWe assessed differences in gross tumor volumes (GTVs) for pancreatic cancer between respiratory-ungated positron emission tomography (3D-PET) and contrast-enhanced four-dimensional computed tomography (CE-4DCT). MATERIALS AND
methodsWe evaluated the GTVs in 21 patients. The sum of the GTVs, which was individually delineated by observers 1 and 2 on the CE-4DCT images from all respiratory phases, was used as GTV-4DCT. The GTVs on the 3D-PET images were extracted with three thresholds: 20%, 30%, and 40% of maximum activity concentration (GTV-n%). We selected one of the GTV-n%, which mostly resembled GTV-4DCT in size, as GTV-PET. Differences in the GTVs were analyzed.
resultsMedian values of GTV-4DCT for observers 1, 2, and GTV-PET were 55.0 mL, 45.7 mL, and 14.6 mL, respectively. GTV-PET was smaller than GTV-4DCT for observers 1 and 2 (p < 0.01 each). Differences of median values of maximum diameters between GTV-4DCT and GTV-PET were 1.7-1.8 cm, 1.4-1.6 cm, and 1.9-2.1 cm in the left-right, anterior-posterior, and craniocaudal directions, respectively.
conclusionGTV-PET based on 3D-PET images was smaller than GTV-4DCT for pancreatic cancer. When we refer to 3D-PET images without CE-4DCT images, we need to pay attention to the above-mentioned finding to contour the GTV.
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