Evidence map›Paper›PMID 30680582›Full record

ArticleGlycoconjugate journal2019

Compositional analysis of the glycosaminoglycan family in velvet antlers of Sika deer (Cervus nippon) at different growing stages.

Naoko Takeda-Okuda, Shuji Mizumoto, Zui Zhang, Soo-Ki Kim, Chi-Ho Lee, Byong-Tae Jeon, Yoshinao Z Hosaka, Kenji Kadomatsu, Shuhei Yamada, Jun-Ichi Tamura

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In one paragraph

Article in Glycoconjugate journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Naoko Takeda-OkudaDepartment of Life and Environmental Agricultural Sciences, Faculty of Agriculture, Tottori University, Tottori, 680-8551, Japan.
Shuji MizumotoDepartment of Pathobiochemistry, Faculty of Pharmacy, Meijo University, Tempaku-ku, Nagoya, 468-8503, Japan.
Zui ZhangDepartment of Biochemistry, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, 466-8550, Japan.
Soo-Ki KimDepartment of Animal Science and Technology, College of Animal Bioscience and Biotechnology, Konkuk University, Kwangjin-gu, Seoul, 143-701, Korea.
Chi-Ho LeeDepartment of Animal Science and Technology, College of Animal Bioscience and Biotechnology, Konkuk University, Kwangjin-gu, Seoul, 143-701, Korea.
Byong-Tae JeonKorea Nokyong Research Center, Konkuk University, Chungju, 380-701, Korea.
Yoshinao Z HosakaVeterinary Anatomy, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, 680-8553, Japan.
Kenji KadomatsuDepartment of Biochemistry, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, 466-8550, Japan.
Shuhei YamadaDepartment of Pathobiochemistry, Faculty of Pharmacy, Meijo University, Tempaku-ku, Nagoya, 468-8503, Japan.
Jun-Ichi TamuraDepartment of Life and Environmental Agricultural Sciences, Faculty of Agriculture, Tottori University, Tottori, 680-8551, Japan. jtamura@tottori-u.ac.jp.ORCID 0000-0002-3957-0479
Konkuk University · KRMeijo University · JPNagoya University · JPTottori University · JPTottori University of Environmental Studies · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycosaminoglycans (GAG) from the velvet antlers of Sika deer (Cervus nippon) at the different growing stages (Fukurozuno, Anshi, and Santajo) of bred and wild deer were isolated and their concentrations and sulfation patterns were analyzed. GAG were digested with chondroitinase ABC, ACI, heparinase-I and -III, and keratanase-II into the corresponding repeating disaccharides of chondroitin sulfate (CS), dermatan sulfate (DS), hyaluronan, heparan sulfate (HS), and keratan sulfate. Cartilaginous tissues contained CS-DS at high concentrations with an almost equal ratio of 4- and 6-sulfates, while 4-sulfate-type CS-DS predominantly occupied ossified tissues, but at low concentrations. High O- and N-sulfation degrees of HS correspond to high ossification. Dynamic quantitative changes in CS-DS and compositional changes in CS-DS and HS were closely associated with the mineralization of deer antlers.

Indexed as

AnimalsAntlersDeerGlycosaminoglycansMaleGlycosaminoglycansChondroitin sulfateDermatan sulfateHeparan sulfateHyaluronanKeratan sulfateVelvet antler

Identifiers

PMID30680582
OpenAlexW2913053141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.