Evidence map›Paper›PMID 30680569›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019

The role of therapy with aminoglycoside in the outcomes of kidney transplant recipients infected with polymyxin- and carbapenem-resistant Enterobacteriaceae.

Maristela P Freire, Doroti de Oliveira Garcia, Ana Paula Cury, Gabriela R Francisco, Nathamy F Dos Santos, Fernanda Spadão, Maria Fernanda Campagnari Bueno, Carlos Henrique Camargo, Flavio J de Paula, Flavia Rossi and 3 more

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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. A meta-analysis for the role of aminoglycosides and tigecyclines in combined regimens against colistin- and carbapenem-resistant Klebsiella pneumoniae bloodstream infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Maristela P FreireWorking Committee for Hospital Epidemiology and Infection Control, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil. maristelapf@uol.com.br.ORCID http://orcid.org/0000-0002-9691-192X
Doroti de Oliveira GarciaBacteriology Center, Adolfo Lutz Institute, São Paulo, Brazil.
Ana Paula CuryMicrobiology Section, Central Laboratory, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Gabriela R FranciscoBacteriology Center, Adolfo Lutz Institute, São Paulo, Brazil.
Nathamy F Dos SantosBacteriology Center, Adolfo Lutz Institute, São Paulo, Brazil.
Fernanda SpadãoWorking Committee for Hospital Epidemiology and Infection Control, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Maria Fernanda Campagnari BuenoBacteriology Center, Adolfo Lutz Institute, São Paulo, Brazil.
Carlos Henrique CamargoBacteriology Center, Adolfo Lutz Institute, São Paulo, Brazil.
Flavio J de PaulaRenal Transplantation Unit, Department of Urology, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Flavia RossiMicrobiology Section, Central Laboratory, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Willian C NahasRenal Transplantation Unit, Department of Urology, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Elias David-NetoRenal Transplantation Unit, Department of Urology, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Ligia C PierrottiDepartment of Infectious Diseases, University of São Paulo School of Medicine Hospital das Clínicas, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstituto Adolfo Lutz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplant recipients are at risk for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Polymyxin-resistant CRE (PR-CRE) infections are especially difficult to treat. The aim of this study was to characterize PR-CRE infections among kidney transplant recipients and identify risk factors for treatment failure. This retrospective cohort study involved all kidney transplant recipients with PR-CRE infection between 2013 and 2017 at our center. Minimal inhibitory concentrations for polymyxin B were determined by broth microdilution. Carbapenem-resistant genes (bla

Indexed as

AdultAgedAmikacinAminoglycosidesAnti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeDrug Resistance, Multiple, BacterialDrug Therapy, CombinationEnterobacteriaceaeEnterobacteriaceae InfectionsEscherichia coliFemaleFosfomycinHumansKidney TransplantationKlebsiella pneumoniaeAmikacinAminoglycosidesAnti-Bacterial AgentsFosfomycinPolymyxinsDouble carbapenemFosfomycinKidney transplantMortalityPolymyxin resistanceTreatment

Identifiers

PMID30680569
OpenAlexW2913120338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.