Evidence map›Paper›PMID 30680318›Full record

ArticleBioengineering & translational medicine2019

Rescuing mesenchymal stem cell regenerative properties on hydrogel substrates post serial expansion.

Varsha V Rao, Michael K Vu, Hao Ma, Anouk R Killaars, Kristi S Anseth

Abstract read
In one paragraph

Article in Bioengineering & translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. MSC Manufacture.Advances in experimental medicine and biology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Implications of Cellular Mechanical Memory in Bioengineering.ACS biomaterials science & engineering · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Varsha V RaoDept. of Chemical and Biological Engineering University of Colorado Boulder CO, 80303.
Michael K VuDept. of Chemical and Biological Engineering University of Colorado Boulder CO, 80303.
Hao MaDept. of Chemical and Biological Engineering University of Colorado Boulder CO, 80303.
Anouk R KillaarsBioFrontiers Institute University of Colorado Boulder CO, 80303.
Kristi S AnsethDept. of Chemical and Biological Engineering University of Colorado Boulder CO, 80303.

Funding

Osteogenic Hydrogel Niches to Promote hMSC Migration and DifferentiationR01DE016523 · NIDCR · UNIVERSITY OF COLORADO AT BOULDER · PI ANSETH, KRISTI S. · 2005 to 2023
$6.2M
FACSAria Fusion Cell SorterS10OD021601 · OD · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2016 to 2016
$599k
Mechanical Dosing Effects on MSCsR21AR067469 · NIAMS · UNIVERSITY OF COLORADO · PI ANSETH, KRISTI S. · 2015 to 2016
$361k
NIAMS NIH HHS R21 AR067469NIDCR NIH HHS R01 DE016523NIH HHS S10 OD021601
6 · The paper itself

Abstract

The use of human mesenchymal stem/stromal cells (hMSCs) in most clinical trials requires millions of cells/kg, necessitating

Indexed as

cell manufacturinghydrogelsmechanotransductionmesenchymal stem cells

Identifiers

PMID30680318
PMCPMC6336661

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.