Evidence map›Paper›PMID 30680294›Full record

ArticleBio-protocol2018

Microirradiation for Precise, Double-strand Break Induction

Kailey E Harrell, Emily Koury, Sarit Smolikove

Open access · greenAbstract read
In one paragraph

Article in Bio-protocol, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Aging Negatively Impacts DNA Repair and Bivalent Formation in theFrontiers in cell and developmental biology · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kailey E HarrellDepartment of Biology, University of Iowa, Iowa City, USA.
Emily KouryDepartment of Biology, University of Iowa, Iowa City, USA.
Sarit SmolikoveDepartment of Biology, University of Iowa, Iowa City, USA.
University of Iowa · US

Funding

An organismal approach to dissecting the mechanism of DSB repair pathway choiceR01GM112657 · NIGMS · UNIVERSITY OF IOWA · PI SMOLIKOVE, SARIT · 2015 to 2019
$1.5M
NIGMS NIH HHS R01 GM112657
6 · The paper itself

Abstract

DNA double-strand breaks (DSBs) are toxic lesions that every cell must accurately repair in order to survive. The repair of DSBs is an integral part of a cell life cycle and can lead to lethality if repaired incorrectly. Laser microirradiation is an established technique which has been used in yeast, mammalian cell culture, and

Indexed as

C. elegansDouble-strand breaksDSB repairLive imagingMicroirradiationProtein recruitment

Identifiers

PMID30680294
PMCPMC6342474
OpenAlexW2903844725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.