Evidence map›Paper›PMID 30680218›Full record

ArticleJournal of intensive care2019

Early mobilisation in mechanically ventilated patients: a systematic integrative review of definitions and activities.

Catherine Clarissa, Lisa Salisbury, Sheila Rodgers, Susanne Kean

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05279547 narecruitingnot on this mapstarted 2023, after this paper: background citation

Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise: A Pilot Study

TypeinterventionalSponsorKU LeuvenRan2023 to 2028Enrolled100ConditionsIntensive Care Unit Acquired Weakness, Critical IllnessArmsConstant-load bed-cycling exercise, Interval bed-cycling exercise
NCT05688267 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Continuous Mobility Training in Individuals With Prolonged Mechanical Ventilation : A Randomized Controlled Trial

TypeinterventionalSponsorTaichung Tzu Chi HospitalRan2023 to 2023Enrolled56ConditionsProlonged Mechanical VentilationArmsContinuous Mobility Training, Usual Care
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
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  7. Trial
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  10. Article
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  13. Review
  14. Saudi Guideline for Mechanical Ventilation in Adults.Saudi journal of medicine & medical sciences · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Inhalation Injury.Seminars in plastic surgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine Clarissa1Department of Nursing Studies, School of Health in Social Science, University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG UK.ORCID 0000-0002-9302-513X
Lisa Salisbury2Division of Dietetics, Nutrition and Biological Sciences, Physiotherapy, Podiatry and Radiography, Queen Margaret University, Queen Margaret University Drive, Musselburgh, EH21 6UU UK.
Sheila Rodgers1Department of Nursing Studies, School of Health in Social Science, University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG UK.
Susanne Kean1Department of Nursing Studies, School of Health in Social Science, University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanically ventilated patients often develop muscle weakness post-intensive care admission. Current evidence suggests that early mobilisation of these patients can be an effective intervention in improving their outcomes. However, what constitutes early mobilisation in mechanically ventilated patients (EM-MV) remains unclear. We aimed to systematically explore the definitions and activity types of EM-MV in the literature.

methodsWhittemore and Knafl's framework guided this review. CINAHL, MEDLINE, EMBASE, PsycINFO, ASSIA, and Cochrane Library were searched to capture studies from 2000 to 2018, combined with hand search of grey literature and reference lists of included studies. The Critical Appraisal Skills Programme tools were used to assess the methodological quality of included studies. Data extraction and quality assessment of studies were performed independently by each reviewer before coming together in sub-groups for discussion and agreement. An inductive and data-driven thematic analysis was undertaken on verbatim extracts of EM-MV definitions and activities in included studies.

resultsSeventy-six studies were included from which four major themes were inferred: (1)

conclusionsThis review highlights the absence of an agreed definition and on what constitutes early mobilisation in mechanically ventilated patients. To advance research and practice an agreed and shared definition is a pre-requisite.

Indexed as

Artificial respirationCritical illnessEarly ambulationEarly mobilisationHumansIntegrative reviewIntensive care unitMechanical ventilatorsRehabilitationReview

Identifiers

PMID30680218
PMCPMC6337811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.