Evidence map›Paper›PMID 30680196›Full record

ReviewMolecular and clinical oncology2019

Prognostic and therapeutic role of HER2 expression in micropapillary carcinoma of the bladder.

Francesca Sanguedolce, Davide Russo, Vito Mancini, Oscar Selvaggio, Beppe Calo, Giuseppe Carrieri, Luigi Cormio

Open access · diamondAbstract readReview
In one paragraph

Review in Molecular and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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  20. Cervical carcinomas with serous-like papillary and micropapillary components: illustrating the heterogeneity of primary cervical carcinomas.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Francesca SanguedolceDepartment of Pathology, University Hospital, I-71121 Foggia, Italy.
Davide RussoDepartment of Pathology, University Hospital, I-71121 Foggia, Italy.
Vito ManciniDepartment of Urology and Renal Transplantation, University Hospital, I-71121 Foggia, Italy.
Oscar SelvaggioDepartment of Urology and Renal Transplantation, University Hospital, I-71121 Foggia, Italy.
Beppe CaloDepartment of Urology and Renal Transplantation, University Hospital, I-71121 Foggia, Italy.
Giuseppe CarrieriDepartment of Urology and Renal Transplantation, University Hospital, I-71121 Foggia, Italy.
Luigi CormioDepartment of Urology and Renal Transplantation, University Hospital, I-71121 Foggia, Italy.
University of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micropapillary carcinoma of the bladder (MPBC) is a variant type of infiltrating urothelial carcinoma, which portends a poor biological behavior in terms of disease stage at first diagnosis and clinical outcome; its peculiar morphology raises issues concerning the ability of tumor detection by imaging techniques and proper biopsy procedure, and the appropriate treatment for non-muscle infiltrating and muscle-infiltrating MPBC remains a matter of debate. On the basis of its established prognostic and therapeutic role in breast and gastro-esophageal cancer in the first instance, the human epidermal growth factor receptor-2 (HER2) has been investigated in selected case series of MPBC over the last 10 years. The aim of the present review was to summarize the existing evidence on HER2 status in MPBC, and to discuss its present and future utility in risk assessment and treatment choice of this uncommon, yet aggressive, disease.

Indexed as

bladder cancerhuman epidermal growth factor receptor-2immunohistochemistryin situ hybridizationmicropapillary variant

Identifiers

PMID30680196
PMCPMC6327213
OpenAlexW2903765325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.