Evidence map›Paper›PMID 30680153›Full record

ArticleAntimicrobial resistance and infection control2019

Assessing the social cost and benefits of a national requirement establishing antibiotic stewardship programs to prevent

R Douglas Scott, Rachel B Slayton, Fernanda C Lessa, James Baggs, Steven D Culler, L Clifford McDonald, John A Jernigan

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. JAC-antimicrobial resistance · 2023
    Article
  4. Review
  5. National Estimates of Healthcare Costs Associated With Multidrug-Resistant Bacterial Infections Among Hospitalized Patients in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

R Douglas Scott1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS H16-3, Atlanta, GA 30329-4027 USA.
Rachel B Slayton1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS H16-3, Atlanta, GA 30329-4027 USA.
Fernanda C Lessa2Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS-C25, Atlanta, GA 30329-4027 USA.
James Baggs1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS H16-3, Atlanta, GA 30329-4027 USA.
Steven D Culler3Department of Health Policy and Management, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322 USA.
L Clifford McDonald1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS H16-3, Atlanta, GA 30329-4027 USA.
John A Jernigan1Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Diseases, Centers for Disease Control and Prevention (CDC), Roybal Campus, 1600 Clifton Road MS H16-3, Atlanta, GA 30329-4027 USA.
Centers for Disease Control and Prevention · USEmory University · USNational Center for Emerging and Zoonotic Infectious Diseases · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgound: Economic evaluations of interventions to prevent healthcare-associated infections in the United States rarely take the societal perspective and thus ignore the potential benefits of morbidity and mortality risk reductions. Using new Department of Health and Human Services guidelines for regulatory impact analysis, we developed a cost-benefit analyses of a national multifaceted, in-hospital Methods: We used a net present value model to assess costs and benefits associated with antibiotic stewardship programs. Model inputs included treatment costs, intervention costs, healthcare-associated Results: From 2015 to 2020, total net benefits of the intervention to the healthcare system range from $300 million to $7.6 billion when values for morbidity and mortality risk reductions are ignored. Including these values, the net social benefits of the intervention range from $21 billion to $624 billion with the annualized net benefit of $25.5 billion under our most likely outcome scenario. Conclusions: Incorporating the economic value of morbidity and mortality risk reductions in economic evaluations of healthcare-associated infections will significantly increase the benefits resulting from prevention.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipClostridioides difficileClostridium InfectionsCross InfectionEconomics, HospitalHumansUnited StatesAnti-Bacterial AgentsAntibiotic stewardshipClostridioides difficile infectionCost-benefit analysisHealthcare-associated infectionsRegulatory impact analysisValue of statistical life

Identifiers

PMID30680153
PMCPMC6343309
OpenAlexW2915068257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.