Evidence map›Paper›PMID 30680023›Full record

ArticleExperimental and therapeutic medicine2019

Coffee brew intake can prevent the reduction of lens glutathione and ascorbic acid levels in HFD-fed animals.

Yosuke Nakazawa, Nana Ishimori, Jun Oguchi, Noriaki Nagai, Masaki Kimura, Megumi Funakoshi-Tago, Hiroomi Tamura

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Caffeine and Vision: Effects on the Eye.Turkish journal of ophthalmology · 2024
    Review
  3. Article
  4. Effects ofTurkish journal of ophthalmology · 2021
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yosuke NakazawaDepartment of Hygienic Chemistry, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Nana IshimoriDepartment of Hygienic Chemistry, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Jun OguchiDepartment of Hygienic Chemistry, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Noriaki NagaiDepartment of Advanced Design for Pharmaceuticals, Faculty of Pharmacy, Kindai University, Osaka 577-8502, Japan.
Masaki KimuraDivision of Pharmacotherapeutics, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Megumi Funakoshi-TagoDepartment of Hygienic Chemistry, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Hiroomi TamuraDepartment of Hygienic Chemistry, Faculty of Pharmacy, Keio University, Tokyo 105-8512, Japan.
Keio University · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The lens has high concentrations of glutathione (GSH) and ascorbic acid (AsA) to maintain redox activity and prevent cataract formation, which is the leading cause of visual impairment worldwide. Metabolic syndrome is reported to be linked with a higher risk of age-associated cataract. As it was demonstrated previously that coffee consumption improved high-fat diet (HFD) -induced metabolic symptoms, it was hypothesized that coffee intake could delay the onset of obesity related-cataract; however, the effect of coffee consumption on this type of cataract remains unknown. Four-week-old male C57BL/6JJms SLC mice were divided into two groups and were provided

Indexed as

ascorbic acidcaffeinecoffeeglutathionepyrocatechol

Identifiers

PMID30680023
PMCPMC6327644
OpenAlexW2904126097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.