ArticleExperimental and therapeutic medicine2019
Correlation of gestational hypertension with abnormal lipid metabolism, insulin resistance and D-dimer and their clinical significance.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- Association Between Total Cholesterol-to-High-Density Lipoprotein Ratio and Gestational Hypertension: A Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Interaction Between Maternal Obesity and Metabolic Dysfunction in Gestational Hypertension and Preeclampsia: A Prospective Birth Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Intergenerational Associations of Hypertensive Disorders of Pregnancy With Offspring Metabolomics: A Systematic Review.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2025Article
- Multi-Omics Reveal That Gut Microbial Dysbiosis Drives Lipid Metabolic Disturbances and Inflammation in Gestational Hypertension.Journal of inflammation research · 2025Article
- Irregularities of Coagulation in Hypertension.Current hypertension reports · 2023Review
- Deficiency of Tregs in hypertension-associated left ventricular hypertrophy.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Increased plasma D-dimer levels may be a promising indicator for diabetic peripheral neuropathy in type 2 diabetes.Frontiers in endocrinology · 2022Article
- Pregnancy and Birth Outcomes during the Early Months of the COVID-19 Pandemic: The MOACC-19 Cohort.International journal of environmental research and public health · 2021Article
- Analysis of risk factors for lower limb deep vein thrombosis in patients after Lumbar Fusion Surgery.Pakistan journal of medical sciencesArticle
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7 authors.
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Abstract
Correlation of gestational hypertension with abnormal lipid metabolism, insulin resistance and D-dimer were investigated. Seventy-three patients with gestational hypertension in Jinhua People's Hospital were selected as the observation group and 70 healthy gestational subjects were selected as the control group. The indexes of lipid metabolism, insulin resistance index [homeostasis model assessment (HOMA)] and the level of D-dimer in the two groups were compared and the correlation of gestational hypertension with the changes in lipid metabolism, insulin resistance and D-dimer was analyzed. The level of HDL-C (high-density lipoprotein cholesterol) in the observation group was significantly lower than that in the control group (P<0.05), while the levels of other indexes were all significantly higher than those in the control group (P<0.05). HOMA index and D-dimer in the observation group were both significantly higher than those in the control group (P<0.05). TG was positively correlated with gestational hypertension (r=0.8767, P<0.01). The correlation analysis of HOMA and gestational hypertension showed positive correlation (r=0.8819, P<0.01). In addition, D-dimer was positively correlated with gestational hypertension (r=0.8933, P<0.01). Lipid metabolism indexes are abnormal in patients with gestational hypertension as well as for insulin resistance index and D-dimer. Besides, the above-mentioned indexes are all correlated with the patients with gestational hypertension. Therefore, more observations should be made on lipid metabolism indexes, insulin resistance and D-dimer in the future treatment of gestational hypertension.
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