ArticleExperimental and therapeutic medicine2019
Role of stress in modulation of skin neurogenic inflammation.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Body image and mental health in chronic skin conditions: A psychosomatic perspective from a systematic review.Applied psychology. Health and well-being · 2025Pooled it
- Review
- Validation of the Utrecht work engagement scale (UWES-9) in the Czech Republic.Scientific reports · 2025Article
- The Skin-Brain Axis: From UV and Pigmentation to Behaviour Modulation.International journal of molecular sciences · 2024Review
- Molecular Mechanisms of Neurogenic Inflammation of the Skin.International journal of molecular sciences · 2023Review
- Comparative effects of capsaicin in chronic obstructive pulmonary disease and asthma (Review).Experimental and therapeutic medicine · 2021Review
- An overview of the tumor microenvironment, from cells to complex networks (Review).Experimental and therapeutic medicine · 2021Review
- Hydroxyurea-induced superinfected ulcerations: Two case reports and review of the literature.Experimental and therapeutic medicine · 2020Article
- Influence of phytochemicals in induced psoriasis (Review).Experimental and therapeutic medicine · 2020Review
- Triamcinolone acetonide induces sterile endophthalmitis in patients with intermediate uveitis: A case report series.Experimental and therapeutic medicine · 2020Article
- Mast cell activation syndromes - evaluation of current diagnostic criteria and laboratory tools in clinical practice (Review).Experimental and therapeutic medicine · 2020Review
- Postanesthetic skin erythema due to succinylcholine versus atracurium.Experimental and therapeutic medicine · 2020Article
- Immunological approaches and therapy in burns (Review).Experimental and therapeutic medicine · 2020Review
- Dynamics of digital ulcers in systemic sclerosis.Experimental and therapeutic medicine · 2020Article
- Influence of inflammation and adipocyte biochemical markers on the components of metabolic syndrome.Experimental and therapeutic medicine · 2020Article
- Assessment of suicidal behavior in dermatology (Review).Experimental and therapeutic medicine · 2020Review
- Skin - a vast organ with immunological function (Review).Experimental and therapeutic medicine · 2020Review
- Autoimmune phenomena in treated and naive pediatric patients with chronic viral hepatitis.Experimental and therapeutic medicine · 2019Article
- Association between personality type, affective distress profile and quality of life in patients with psoriasis vs. patients with cardiovascular disease.Experimental and therapeutic medicine · 2019Article
- Capsaicin: Effects on the Pathogenesis of Hepatocellular Carcinoma.Molecules (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are complex interconnections between the nervous system and the skin highlighted by the impact of stress and neuroendocrine factors on various dermatological conditions. We investigated the influence of stress on skin neurogenic inflammation induced by capsaicin. A total of 31 healthy subjects were randomized into two groups: subjects in the stress group underwent a stress-inducing protocol and those in the control group were exposed to indifferent conditions. Subsequently, topical capsaicin cream was administered on the non-dominant anterior forearm of each subject from the two groups. The assessment of the local inflammatory reaction induced by capsaicin was performed by thermography at 25 and 40 min post-application. In both groups the inflammatory reaction induced by capsaicin was evidenced at 25 min and was maintained at 40 min post-application. However, at 40 min post-application the hyperthermal area was larger in subjects from the stress group, suggesting that stress exposure is associated with an amplification of the mechanisms involved in capsaicin-induced skin neurogenic inflammation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.