Evidence map›Paper›PMID 30679953›Full record

ArticleEcancermedicalscience2018

ReDO_DB: the repurposing drugs in oncology database.

Pan Pantziarka, Ciska Verbaanderd, Vidula Sukhatme, I Rica Capistrano, Sergio Crispino, Bishal Gyawali, Ilse Rooman, An Mt Van Nuffel, Lydie Meheus, Vikas P Sukhatme and 1 more

Abstract read
In one paragraph

Article in Ecancermedicalscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Trial
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  12. Article
  13. Drug Repurposing for Cancer Treatment: A Comprehensive Review.International journal of molecular sciences · 2024
    Review
  14. Article
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pan PantziarkaThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Ciska VerbaanderdThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Vidula SukhatmeGlobalCures Inc., Newton, MA 02459 USA.
I Rica CapistranoThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Sergio CrispinoThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Bishal GyawaliThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Ilse RoomanThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
An Mt Van NuffelThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Lydie MeheusThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.
Vikas P SukhatmeGlobalCures Inc., Newton, MA 02459 USA.
Gauthier BoucheThe Anticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project.org/db/).

Indexed as

cancer drugsdrug repurposingonline databaseReDO projectrepositioning

Identifiers

PMID30679953
PMCPMC6345075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.