ArticleJournal of pain research2019
Celiac plexus block increases quality of life in patients with pancreatic cancer.
Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07117032 (A Prospective Pilot Clinical Trial of Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Pilot Clinical Trial of Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
Who cites it
7 citing papers in PubMed, 27 citations in OpenAlex.
- Celiac plexus radiosurgery for retroperitoneal pain in advanced cancer: a pre-specified secondary analysis of health-related quality of life in a phase II single-arm trial.EClinicalMedicine · 2026Article
- Celiac plexus block and neurolysis procedure: treatment of chronic pain in pancreatic cancer.Pain management · 2025Article
- Development of updated population norms for the SF-36 for Hungary and comparison with 1997-1998 norms.Health and quality of life outcomes · 2025Article
- Analgesia for Gynecologic Oncologic Surgeries: A Narrative Review.Current pain and headache reports · 2022Review
- Interventional Treatments for Cancer Pain.Cancer treatment and research · 2021Article
- A Comprehensive Review of the Celiac Plexus Block for the Management of Chronic Abdominal Pain.Current pain and headache reports · 2020Review
- Ablative 5-Fraction Stereotactic MRI-Guided Adaptive Radiotherapy for Oligometastatic Pancreatic Adenocarcinoma.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPancreatic cancer is a malignant disease with a high mortality rate and severe pain that is challenging to manage. To reduce the excruciating abdominal pain, opioids and adjuvant agents are conventionally used.
objectivesPRNCPB is a treatment of neural therapy. The number of studies assessing the effect on patients' QoL is limited and inconsistent. With this study, we intended to address this issue. STUDY
designA prospective nonrandomized study with a series of cases of unresectable pancreatic cancer was conducted.
settingThe study was performed at our pain clinic under real life conditions. MATERIALS AND
methodsA total number of 16 patients with severe abdominal pain were enrolled in the study all of whom had responded to combined systemic analgesic therapy inadequately and had intolerable side effects contraindicating further increase in dose. The efficacy of this invasive, palliative analgesic procedure was evaluated 35 days after PRNCPB was performed. Primary outcomes were changed in pain intensity using the VAS questionnaire. Secondary outcomes were improved in QoL using the SF-36 questionnaire. Changes in pain medications and adverse reactions were monitored.
resultsAfter PRNCPB patients experienced a significant decrease ( LIMITATIONS: Detection, observation, and reporting bias can be estimated as moderate. Selection bias was not detected.
conclusionOur results give preliminary evidence that PRNCPB might be helpful as an additional treatment to conventional pain management in end-stage pancreatic cancer patients. PRNCPB seems to improve QoL in these patients in a time frame of at least 5 weeks after intervention.
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