Evidence map›Paper›PMID 30679891›Full record

ArticleJournal of stem cells & regenerative medicine2018

Intra-arterial Transplantation of Human Umbilical Cord Blood Mononuclear Cells in Sub-acute Ischemic Stroke Increases VEGF Expression in Rats.

Yetty Ramli, Ahmad Sulaiman Alwahdy, Mohammad Kurniawan, Berry Juliandi, Puspita Eka Wuyung

Open access · goldAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of stem cells & regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yetty RamliNeurology Department , Medical Faculty University of Indonesia/Ciptomangunkusumo National Hospital, Indonesia.
Ahmad Sulaiman AlwahdyNeurology Department , Medical Faculty University of Indonesia/Ciptomangunkusumo National Hospital, Indonesia.
Mohammad KurniawanNeurology Department , Medical Faculty University of Indonesia/Ciptomangunkusumo National Hospital, Indonesia.
Berry JuliandiBiology Department, Institut Pertanian Bogor, Indonesia.
Puspita Eka WuyungPathology Anatomy Department,University of Indonesia/Ciptomangunkusumo National Hospital, Indonesia.
University of Indonesia · IDIPB University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombolysis (rt-PA) is the only United States Food and Drug Administration (FDA) approved drug currently available. Unfortunately, its effect has been limited by the narrow therapeutic time window. Human cord blood mononuclear cells (cbMNC) is a promising treatment for ischemic stroke by forming collateral and neo-vascularization where it is one of the important factors that contribute to cell repair. Therefore, evaluation of neo-vascularization in sub-acute stroke may be beneficial for recovery. One group for healthy rat and three groups (n=6 per group) of male wistar rats have undergone permanent middle cerebral artery occlusion (MCAO). Transplantation 1x10

Indexed as

AngiogenesisHuman umbilical cord bloodMononuclear cellsNeurogenesisRats

Identifiers

PMID30679891
PMCPMC6339975
OpenAlexW3004381681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.