Evidence map›Paper›PMID 30679798›Full record

ArticleLeukemia2019

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia.

Christopher F Krombholz, Lorena Gallego-Villar, Sushree S Sahoo, Pritam K Panda, Marcin W Wlodarski, Konrad Aumann, Mark Hartmann, Daniel B Lipka, Michael Daskalakis, Christoph Plass and 3 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Review
  7. Pediatric Neoplasms Presenting with Monocytosis.Current hematologic malignancy reports · 2021
    Review
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Christopher F KrombholzDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Lorena Gallego-VillarDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sushree S SahooDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Pritam K PandaDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-4879-2302
Marcin W WlodarskiDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-6638-9643
Konrad AumannDepartment of Pathology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Mark HartmannDivision of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-4072-4658
Daniel B LipkaDivision of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-5081-7869
Michael DaskalakisDivision of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.
Christoph PlassGerman Cancer Consortium, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-2554-3952
Charlotte M NiemeyerDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Miriam ErlacherDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Christian FlothoDivision of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. christian.flotho@uniklinik-freiburg.de.
University of Freiburg · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimetabolites, AntineoplasticAzacitidineCarcinogenesisHumansLeukemia, Myelomonocytic, JuvenileMesenchymal Stem CellsMiceMice, Inbred BALB CNeoplastic Stem CellsTumor Cells, CulturedXenograft Model Antitumor AssaysAntimetabolites, AntineoplasticAzacitidine

Identifiers

PMID30679798
OpenAlexW2912775647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.