ArticleScientific reports2019
Regulation of volatile and non-volatile pheromone attractants depends upon male social status.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Social Context Alters Chemical Signalling and Endocrine Profiles in Two Mouse Subspecies.Journal of chemical ecology · 2026Article
- Male and female mice scent mark during social communication regardless of sexual motivation or partner identity.Cell reports · 2026Article
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- Major urinary protein (Microbiology spectrum · 2024Article
- Connectivity and molecular profiles of Foxp2- and Dbx1-lineage neurons in the accessory olfactory bulb and medial amygdala.The Journal of comparative neurology · 2024Article
- Increased paternal corticosterone exposure influences offspring behaviour and expression of urinary pheromones.BMC biology · 2023Article
- Variation in mouse chemical signals is genetically controlled and environmentally modulated.Scientific reports · 2023Article
- Female scent accelerates growth of juvenile male mice.Scientific reports · 2023Article
- Sex-dependent control of pheromones on social organization within groups of wild house mice.Current biology : CB · 2023Article
- Attraction of female house mice to male ultrasonic courtship vocalizations depends on their social experience and estrous stage.PloS one · 2023Article
- Perioral secretions enable complex social signaling in African mole-rats (genus Fukomys).Scientific reports · 2022Article
- Regulation of Sexually Dimorphic Expression of Major Urinary Proteins.Frontiers in physiology · 2022Review
- Pheromones that correlate with reproductive success in competitive conditions.Scientific reports · 2021Article
- Male pheromones and their reception by females are co-adapted to affect mating success in two subspecies of brown rats.Current zoology · 2021Article
- Lymphocytic Choriomeningitis Virus Alters the Expression of Male Mouse Scent Proteins.Viruses · 2021Article
- Molecular identification of an androgen receptor and the influence of long-term aggressive interaction on hypothalamic genes expression in black rockfish (Sebastes schlegelii).Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
- Biological Roles of Lipocalins in Chemical Communication, Reproduction, and Regulation of Microbiota.Frontiers in physiology · 2021Review
- Conspecific recognition of pedal scent in domestic dogs.Scientific reports · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
We investigated the regulation of chemical signals of house mice living in seminatural social conditions. We found that male mice more than doubled the excretion of major urinary proteins (MUPs) after they acquired a territory and become socially dominant. MUPs bind and stabilize the release of volatile pheromone ligands, and some MUPs exhibit pheromonal properties themselves. We conducted olfactory assays and found that female mice were more attracted to the scent of dominant than subordinate males when they were in estrus. Yet, when male status was controlled, females were not attracted to urine with high MUP concentration, despite being comparable to levels of dominant males. To determine which compounds influence female attraction, we conducted additional analyses and found that dominant males differentially upregulated the excretion of particular MUPs, including the pheromone MUP20 (darcin), and a volatile pheromone that influences female reproductive physiology and behavior. Our findings show that once male house mice become territorial and socially dominant, they upregulate the amount and types of excreted MUPs, which increases the intensities of volatiles and the attractiveness of their urinary scent to sexually receptive females.
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