ArticleBMJ open2019
Impact of surgical site infection (SSI) following gynaecological cancer surgery in the UK: a trainee-led multicentre audit and service evaluation.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Prevalence of surgical site infection and its associated factors after cesarean section in Ethiopia: systematic review and meta-analysis.BMC pregnancy and childbirth · 2020Pooled it
- Observational
- Can We Lower the Burden of Antimicrobial Resistance (AMR) in Heavily Immunocompromised Patients? A Narrative Review and Call to Action.Infectious diseases and therapy · 2025Review
- The Relation Between Post-Operative Surgical Site Infection and Time to Start Adjuvant Treatment in Ovarian and Uterine Cancers.Current oncology (Toronto, Ont.) · 2025Article
- Review
- Light-based therapy of infected wounds: a review of dose considerations for photodynamic microbial inactivation and photobiomodulation.Journal of biomedical optics · 2025Review
- Relationship between pre-operative glycated haemoglobin and surgical site infection in patients undergoing elective colon cancer surgery.Oncology letters · 2022Article
- Systematic review and meta-analysis of the risk factors of surgical site infection in patients with colorectal cancer.Translational cancer research · 2022Article
- Surgical Site Infections in patients undergoing major oncological surgery during the COVID-19 paNdemic (SCION): A propensity-matched analysis.Journal of surgical oncology · 2022Article
- Dual antibiotic prevention bundle is associated with decreased surgical site infections.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2020Article
- Risk factors of health care-associated infection in elderly patients: a retrospective cohort study performed at a tertiary hospital in China.BMC geriatrics · 2019Article
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Authors and funding
21 authors at 14 institutions in 1 country.
Funding
Abstract
objectivesSurgical site infection (SSI) complicates 5% of all surgical procedures in the UK and is a major cause of postoperative morbidity and a substantial drain on healthcare resources. Little is known about the incidence of SSI and its consequences in women undergoing surgery for gynaecological cancer. Our aim was to perform the first national audit of SSI following gynaecological cancer surgery through the establishment of a UK-wide trainee-led research network. DESIGN AND
settingIn a prospective audit, we collected data from all women undergoing laparotomy for suspected gynaecological cancer at 12 specialist oncology centres in the UK during an 8-week period in 2015. Clinicopathological data were collected, and wound complications and their sequelae were recorded during the 30 days following surgery.
resultsIn total, 339 women underwent laparotomy for suspected gynaecological cancer during the study period. A clinical diagnosis of SSI was made in 54 (16%) women. 33% (18/54) of women with SSI had prolonged hospital stays, and 11/37 (29%) had their adjuvant treatment delayed or cancelled. Multivariate analysis found body mass index (BMI) was the strongest risk factor for SSI (OR 1.08[95% CI 1.03 to 1.14] per 1 kg/m
conclusionsSSI is common in women undergoing surgery for gynaecological cancer leading to delays in discharge and adjuvant treatment. Resultant delays in adjuvant treatment may impact cancer-specific survival rates. Modifiable factors, such as choice of wound closure material, offer opportunities for reducing SSI and reducing morbidity in these women. There is a clear need for new trials in SSI prevention in this patient group; our trainee-led initiative provides a platform for their successful completion.
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