ArticleGenetics2019
Detecting Adaptive Differentiation in Structured Populations with Genomic Data and Common Gardens.
Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Selection shapes the evolution of genome size in a globally invasive plant.The New phytologist · 2026Article
- A method for identifying local adaptation in structured populations.PLoS genetics · 2025Article
- Evaluating the roles of drift and selection in trait loss along an elevational gradient.Evolution; international journal of organic evolution · 2025Article
- Article
- Error rates in QST-FST comparisons depend on genetic architecture and estimation procedures.Genetics · 2025Article
- Genetic diversity and environmental adaptation in Ethiopian tef.G3 (Bethesda, Md.) · 2025Article
- Error rates inbioRxiv : the preprint server for biology · 2024Article
- Article
- Evolutionary Analyses of Gene Expression Divergence in Panicum hallii: Exploring Constitutive and Plastic Responses Using Reciprocal Transplants.Molecular biology and evolution · 2023Article
- Article
- Ghat: an R package for identifying adaptive polygenic traits.G3 (Bethesda, Md.) · 2023Article
- Local adaptation: Causal agents of selection and adaptive trait divergence.Annual review of ecology, evolution, and systematics · 2022Article
- Article
- Using singleton densities to detect recent selection inEvolution letters · 2021Article
- Molecular Parallelism Underlies Convergent Highland Adaptation of Maize Landraces.Molecular biology and evolution · 2021Article
- The ecological, genetic and genomic architecture of local adaptation and population differentiation inProceedings. Biological sciences · 2021Article
- Local adaptation contributes to gene expression divergence in maize.G3 (Bethesda, Md.) · 2021Article
- Genome size evolution: towards new model systems for old questions.Proceedings. Biological sciences · 2020Article
- Parallel flowering time clines in native and introduced ragweed populations are likely due to adaptation.Ecology and evolution · 2020Article
- 275 years of forestry meets genomics inEvolutionary applications · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Adaptation in quantitative traits often occurs through subtle shifts in allele frequencies at many loci-a process called polygenic adaptation. While a number of methods have been developed to detect polygenic adaptation in human populations, we lack clear strategies for doing so in many other systems. In particular, there is an opportunity to develop new methods that leverage datasets with genomic data and common garden trait measurements to systematically detect the quantitative traits important for adaptation. Here, we develop methods that do just this, using principal components of the relatedness matrix to detect excess divergence consistent with polygenic adaptation, and using a conditional test to control for confounding effects due to population structure. We apply these methods to inbred maize lines from the United States Department of Agriculture germplasm pool and maize landraces from Europe. Ultimately, these methods can be applied to additional domesticated and wild species to give us a broader picture of the specific traits that contribute to adaptation and the overall importance of polygenic adaptation in shaping quantitative trait variation.
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