Evidence map›Paper›PMID 30679225›Full record

ArticleAJNR. American journal of neuroradiology2019

A 3T Phase-Sensitive Inversion Recovery MRI Sequence Improves Detection of Cervical Spinal Cord Lesions and Shows Active Lesions in Patients with Multiple Sclerosis.

A Fechner, J Savatovsky, J El Methni, J C Sadik, O Gout, R Deschamps, A Gueguen, A Lecler

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Accuracy of Noncontrast T2 SPACE in Active MS Cord Lesion Detection.AJNR. American journal of neuroradiology · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A FechnerFrom the Departments of Neuroradiology (A.F., J.S., J.C.S., A.L.).ORCID 0000-0003-0801-6341
J SavatovskyFrom the Departments of Neuroradiology (A.F., J.S., J.C.S., A.L.).ORCID 0000-0002-6732-1779
J El MethniLaboratoire MAP5, UMR CNRS 8145 (J.E.M.), Université Paris Descartes, Paris, France.ORCID 0000-0003-2947-3496
J C SadikFrom the Departments of Neuroradiology (A.F., J.S., J.C.S., A.L.).ORCID 0000-0003-1429-5631
O GoutNeurology (O.G., R.D., A.G.), Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.ORCID 0000-0001-6435-0761
R DeschampsNeurology (O.G., R.D., A.G.), Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.ORCID 0000-0001-6291-8771
A GueguenNeurology (O.G., R.D., A.G.), Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.ORCID 0000-0001-5170-5818
A LeclerFrom the Departments of Neuroradiology (A.F., J.S., J.C.S., A.L.) alecler@for.paris.ORCID 0000-0001-7869-1815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMagnetic Resonance Imaging is the modality of choice to detect spinal cord lesions in patients with Multiple Sclerosis (MS). However, this imaging is challenging. New sequences such as phase-sensitive inversion recovery have been developed to improve detection. Our aim was to compare a 3D phase-sensitive inversion recovery and a conventional imaging dataset including postcontrast T2WI and T1WI to detect MS spinal cord lesions. MATERIALS AND

methodsThis retrospective single-center study included 100 consecutive patients with MS (mean age, 41 years) from January 2015 to June 2016. One senior neuroradiologist and 1 junior radiologist blinded to clinical data checked for new spinal cord lesions, individually analyzing conventional and 3D phase-sensitive inversion recovery datasets separately, placing a 3-week delay between the 2 readings. A consensus reading was done with a third senior neuroradiologist. A Wilcoxon test was used to compare the 2 imaging datasets. Intra- and interobserver agreement was assessed by the κ coefficient.

results3D phase-sensitive inversion recovery detected significantly more lesions than conventional imaging (480 versus 168,

conclusionsOur study showed that 3D phase-sensitive inversion recovery significantly improved detection of cervical spinal cord lesions, including both enhancing and nonenhancing lesions in patients with MS.

Indexed as

AdultCervical CordFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisNeuroimagingRetrospective Studies

Identifiers

PMID30679225
PMCPMC7028618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.