Evidence map›Paper›PMID 30679204›Full record

ArticleMolecular pharmacology2019

Tosifa Memon, Oleg Yarishkin, Christopher A Reilly, David Križaj, Baldomero M Olivera, Russell W Teichert

Open access · bronzeAbstract read
In one paragraph

Article in Molecular pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. State-Dependent Blockade of Dorsal Root Ganglion Voltage-Gated NaInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tosifa MemonDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah tosifa.memon@utah.edu.ORCID 0000-0003-0453-9436
Oleg YarishkinDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah.
Christopher A ReillyDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah.
David KrižajDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah.
Baldomero M OliveraDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah.
Russell W TeichertDepartments of Biology (T.M., B.M.O., R.W.T.), Pharmacology and Toxicology (T.M., C.A.R.), and Ophthalmology and Visual Sciences (O.Y., D.K.), University of Utah, Salt Lake City, Utah.
University of Utah · US

Funding

Venoms, Biological Resources, Molecular BiologyP01GM048677 · NIGMS · UNIVERSITY OF UTAH · PI OLIVERA, BALDOMERO M · 1993 to 2018
$32.2M
University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6M
TRP Channels and Air PollutionR01ES017431 · NIEHS · UNIVERSITY OF UTAH · PI REILLY, CHRISTOPHER A · 2009 to 2024
$5.3M
Replacement of the Flexcell Tension systemR01EY027920 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ · 2017 to 2026
$3.5M
The role of mechanosensation in the vertebrate retinaR01EY022076 · NEI · UNIVERSITY OF UTAH · PI KRIZAJ, DAVID · 2013 to 2017
$1.9M
NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY022076NEI NIH HHS R01 EY027920NIEHS NIH HHS R01 ES017431NIGMS NIH HHS P01 GM048677
6 · The paper itself

Abstract

Transient receptor potential (TRP) cation channels are molecular targets of various natural products. TRPA1, a member of TRP channel family, is specifically activated by natural products such as allyl isothiocyanate (mustard oil), cinnamaldehyde (cinnamon), and allicin (garlic). In this study, we demonstrated that TRPA1 is also a target of

Indexed as

Allylbenzene DerivativesAnimalsAnisolesCalcium ChannelsFoeniculumHEK293 CellsHumansIsothiocyanatesMiceMice, Inbred C57BLOils, VolatileSensory Receptor CellsSpinal Nerve RootsTransient Receptor Potential ChannelsTrigeminal GanglionTRPA1 Cation ChannelAllylbenzene Derivativesallyl isothiocyanateanetholeAnisolesCalcium Channelsfennel oil, bitterIsothiocyanatesOils, VolatileTransient Receptor Potential ChannelsTRPA1 Cation ChannelTRPA1 protein, human

Identifiers

PMID30679204
PMCPMC6408737
OpenAlexW2914190263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.